搜索结果: 76-84 共查到“药学 肿瘤药物”相关记录84条 . 查询时间(0.133 秒)
武汉地区抗肿瘤药物应用趋势分析
抗肿瘤药物 临床应用
2013/9/26
了解武汉地区抗肿瘤药物的临床应用情况,探讨近年来该类药品的应用趋势.方法:以抗肿瘤药市场销售金额的变化为基础,对1999～2001年抗肿瘤药的临床应用情况进行统计分析.结果:抗肿瘤药销售金额占全类药品总金额的比例逐年增加,其中抗代谢类药品的消费呈增长趋势,抗肿瘤中草药占抗肿瘤药销售的40%以上,增长率保持在16%以上;进口抗肿瘤药消费增长迅速.结论:抗肿瘤药品的需求将继续扩大,国产药品的主导消费地...
目的 研究格尔德霉素(Geldanamycin ,GDM)对人肝癌BEL-7402细胞周期的影响及顺铂和丝裂霉素C等药物联用GDM后的体外体内抗肿瘤作用。方法 用MTT法检测药物对肝癌BEL-7402细胞的生长抑制作用;流式细胞术分析细胞周期;小鼠移植性肝癌22模型研究药物的体内抗肿瘤作用。结果 MTT法测得GDM对BEL7402细胞的生长抑制作用IC50为0.28μmol·L-1。GDM 0.1...
双(2,6-哌嗪二酮)类抗肿瘤药物的研究:2,3-二乙酰氧基-1,4-二(3′,5′-二酮-N4′-取代哌嗪甲基)苯的合成
3-二乙酰氧基-1 4-二(3′5′-二酮-N4′-取代哌嗪甲基)苯 体外抗肿瘤试验
2010/2/25
Seventeen compounds having the structure of 2,3-diacetoxy-1,4-bis(3′,5′- dioxo-N4′-substituted piperazinyl methyl)benzene were designed and synthesized based on chelation hypothesis. Their antitumor a...
In order to search for potential antitumor drugs of piperazincs,1-(3-chloro-2- hydroxypropyl)-4,4-dialkylpiperazine bromides(Va～g)were prepared.In preliminary toxicity and antitumor activity tests com...
哌嗪类抗肿瘤药物研究:双哌嗪双季铵盐类化合物的合成
双哌嗪双季铵盐 抗肿瘤药物
2010/2/25
Ten compounds of dipiperazine diquaternary ammoniums were synthesized from1-benzoylpiperazine by N-alkylation , quaternization and debenzoylation. The results of toxicitv andantitumor activity tests s...
抗肿瘤药物研究 去甲斑蝥素氨基酸衍生物的合成与抗癌活性
去甲斑蝥素 氨基酸衍生物 Bel-4702 抗癌活性
2010/3/1
In order to search for new compounds with higher anti-cancer activities and lower toxicities, 19 amino acid derivatives of norcantharidin, of which 16 are unknown compounds, were designed and synthesi...
抗肿瘤药物的研究:N′,N″-二螺三哌嗪类化合物的合成
抗肿瘤药 N′,N″-二螺三哌嗪
2010/3/3
In order to search for new antitumor drugs, sixteen N′, N″-dispirotripiperazine derivatives were synthesized from N′, N″-dispirotripiperazinium dichloride dihydrochloride by substitution, acylation an...