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Purpose: The aim of this study was to observe the effects of and compliance with an intensive insulin regimen in preadolescent children with type-1 diabetes. Patients and methods: Eleven insulin-depen...
Diabetes causes metabolic defects and related vascular alterations such as atherosclerosis. These vascular alterations may also reflect the renal structural degeneration under the influence of diabete...
Background: It is only recently that the knowledge of dermatoglyphics has been applied to the field of medical and genetic diagnosis. Aim: The aim of the present study was to compare and evaluate the ...
Aim: This study was conducted to assess the impact of a brief, patient-centered education program on perceived self-efficacy and attitudes towards diabetes of patients with type 2 diabetes.
Aim: It is generally accepted that proinflammatory cytokines secreted by mononuclear cells are responsible for pancreatic beta (B) cell destruction in animal models of autoimmune type-1 diabetes melli...
Aim: The association between oxidative stress and diabetic complications is well known. The main goal of antidiabetic therapy is to prevent the complications of diabetes. Gliclazide (sulfonylurea) and...
Aims: The aim of this study was to evaluate postural stability and functional capacity in recreational athletes with type 1 diabetes mellitus (T1 DM) and to compare them with healthy recreational athl...
Aims: It is known that there is a relationship between diabetic complications and chronic inflammation characterized by alterations in circulating acute phase proteins. It has been emphasized that inf...
Background: Post-transplant diabetes mellitus (PTDM) contributes to the risk for cardiovascular diseases and infection, reducing graft and patient survival. This study was conducted to identify the in...
对1999~2000年门诊及住院的家族高发性2型糖尿病患者为先证者的136个大家系进行研究,以探讨该病的遗传模式。对家系人群采用Falconer 法估算遗传率,用Penrose法进行多基因分析,并用S.A.G.E-REGD软件拟合A型回归Logistic模型进行复合分离分析的方法,对家族高发性2型糖尿病家系进行研究。结果表明,136个大家系的2型糖尿病遗传率为94.07%±5.84%,提示在这些家...
摘要 研 究磺酰脲类受体1(SUR1)基因外显子16-3c/t多态性在中国某南方汉族人群中是否为2型糖尿病的致病基因座。采用聚合酶链反应-限制酶酶切片段长度多态性(PCR-RFLP)方法对南方汉族46个2型糖尿病高发家系成员的SUR1基因外显子16的多态性进行分析。利用Mantel-Haenszel分层分析研究该基因座多态性与2型糖尿病的关系。在高发家系人群中,SUR1基因外显子16-3c/t多...
摘要解偶联蛋白(UCPs)是线粒体内膜上的一种转运蛋白,它能够降低线粒体内膜上的质子梯度,使底物氧化和ADP磷酸化解偶联,减少ATP的产生。基于其功能,解偶联蛋白基因被视为肥胖病及2型糖尿病的重要候选基因。UCP同系物过表达的遗传工程小鼠表现出对饮食导致的肥胖具有耐受性,同时UCP2基因3'非翻译区的45bp插入/缺失以及UCP3基因C-55T多态与肥胖表型的相关性等研究结论支持这一假说。本文对U...
期刊信息 篇名 Adipocyte lipid diabetes Diabetes, Lipids and Adipocyte Secretagogues 语种 英文 撰写或编译 撰写 作者 May Faraj,LU Hui-ling,Cianflone K 第一作者单位 May Faraj,Cianflone K.Laboratory for Cardiovascular Research, R...
期刊信息 篇名 Roles of adipocyte derived hormone adiponectin and resistin in insulin resistance of type 2 Diabetes 语种 英文 撰写或编译 撰写 作者 Hui-Ling LU,Hong-Wei Wang,Yu Wen,Mu-Xun Zhang,Han-Hua Lin 第一作者单位 Hui-Ling...
4 December 2006,Speaking at the 19th World Diabetes Congress in Cape Town, South Africa, Giancarlo Viberti, Professor of Diabetes and Metabolic Medicine at King's, outlined the findings of the ADOPT s...

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