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Is Stat3 and/or p53 mRNA expression a prognostic marker for renal cell carcinoma?
Stat3 p53 mRNA cell carcinoma
2009/12/16
Signal transducer and activator of transcription (Stat) 3 and p53 integrate upstream signals, and are positive and negative regulators of tumor cell proliferation, respectively. Stat3 and p53 also neg...
Repeated regression of pulmonary metastases from renal cell carcinoma after treatment using different interferon-alpha preparations
pulmonary metastases renal cell carcinoma interferon-alpha preparations
2009/3/2
A 49-year-old man with pulmonary metastasis from renal cell carcinoma (RCC) was treated with recombinant IFN-α2b (Intron A®). A complete response was achieved within 4 months and thereafter pers...
Possible role of the RhoC/ROCK pathway in progression of clear cell renal cell carcinoma
RhoC/ROCK pathway clear cell renal cell carcinoma
2009/3/2
To clarify the role of the Rho small GTP-binding protein (Rho) and its major downstream target, ROCK (Rho-associated serine-threonine protein kinase), in progression of renal cell carcinoma (RCC), w...
Significant association of interleukin 10 receptor mRNA levels with renal cell carcinoma metastasis
mRNA renal cell carcinoma metastasis
2009/3/2
Immunosuppressive cytokine, interleukin 10 (IL-10), is associated with progression of the renal cell carcinoma (RCC). However, the roles of its cell surface receptor, interleukin 10 receptor (IL-10R...