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Lower systolic blood pressure at age 7 y in low-birth-weight children who received iron supplements in infancy: results from a randomized controlled trial
Barker hypothesis blood pressure cardiovascular risk early programming hypertension iron supplementation low birth weight
2018/11/15
Background: Low birth weight (LBW) (≤2500 g) is associated with iron deficiency in infancy and high blood pressure (BP) later in life.
Dietary iron intake, iron status, and gestational diabetes
gestational diabetes mellitus dietary iron iron status pregnancy ron supplementation
2018/11/21
Pregnant women are particularly vulnerable to iron deficiency and related adverse pregnancy outcomes and, as such, are routinely recommended for iron supplementation. Emerging evidence from both anima...
Iron status of young children in Europe
iron deficiency, iron deficiency anemia, iron repletion, iron intake, young children, Europe, cow milk, formula, human milk
2018/11/21
Iron deficiency (ID) is common in young children aged 6–36 mo. Although the hazards associated with iron deficiency anemia (IDA) are well known, concerns about risks associated with excess iron intake...
Iron status of North American pregnant women: an update on longitudinal data and gaps in knowledge from the United States and Canada
pregnancy anemia hemoglobin ferritin inflammation erythropoietin serum transferrin receptor hepcidin
2018/11/21
Pregnant women are particularly vulnerable to iron deficiency due to the high iron demands of pregnancy. To avoid the adverse birth outcomes that are associated with maternal iron deficiency anemia, b...
Iron status of toddlers, nonpregnant females, and pregnant females in the United States
ferritin soluble transferrin receptor total-body iron iron deficiency toddlers women of reproductive age hemoglobin
2018/11/21
Background: Total-body iron stores (TBI), which are calculated from serum ferritin and soluble transferrin receptor concentrations, can be used to assess the iron status of populations in the United S...
Iron status of North American pregnant women: an update on longitudinal data and gaps in knowledge from the United States and Canada
pregnancy anemia hemoglobin ferritin inflammation erythropoietin serum transferrin receptor hepcidin
2018/11/22
Pregnant women are particularly vulnerable to iron deficiency due to the high iron demands of pregnancy. To avoid the adverse birth outcomes that are associated with maternal iron deficiency anemia, b...
Assessment of iron status in settings of inflammation: challenges and potential approaches
infection inflammation iron status preschool children serum ferritin soluble transferrin receptor total-body iron stores women of reproductive age
2018/11/21
The determination of iron status is challenging when concomitant infection and inflammation are present because of confounding effects of the acute-phase response on the interpretation of most iron in...
Impact of chronic and acute inflammation on extra- and intracellular iron homeostasis
acute phase response C-reactive protein ferroportin hepatocyte hepcidin infancy intra- and extracellular pathogens macrophage pregnancy
2018/11/21
Inflammation has a major impact on iron homeostasis. This review focuses on acute and chronic inflammation as it affects iron trafficking and, as a result, the availability of this essential micronutr...
During pregnancy, iron needs to increase substantially to support fetoplacental development and maternal adaptation to pregnancy. To meet these iron requirements, both dietary iron absorption and the ...
Gaps in evidence regarding iron deficiency anemia in pregnant women and young children: summary of US Preventive Services Task Force recommendations
iron pregnant women screening supplementation young children
2018/11/21
The US Preventive Services Task Force (USPSTF) makes recommendations to primary care providers regarding preventive services for asymptomatic patients. Recommendations are based on the scientific evid...
Introduction to workshop on iron screening and supplementation in iron-replete pregnant women and young children
iron pregnancy infancy young childhood iron screening iron supplementation
2018/11/21
The NIH Office of Dietary Supplements convened a public workshop on iron screening and supplementation in iron-replete pregnant women and young children in 2016 in Bethesda, Maryland. The starting poi...
Tackling iron deficiency in infants: galacto-oligosaccharides may be up to the task
iron deficiency galacto-oligosaccharides in infants
2018/11/19
Iron, an essential trace element, plays a critical role in maintaining health by mediating mitochondrial function and DNA synthesis and repair and serving as a critical factor for key enzymes (1). In ...
Iron deficiency and anemia are prevalent in women with multiple gestations
anemia hepcidin iron deficiency multiple births pregnancy
2018/12/14
Background: Little attention has been placed on the unique iron demands that may exist in women with multiple gestations. This merits attention because iron deficiency (ID) during pregnancy is associa...
Iron deficiency and anemia are prevalent in women with multiple gestations
anemia hepcidin iron deficiency multiple births pregnancy
2018/12/18
Background: Little attention has been placed on the unique iron demands that may exist in women with multiple gestations. This merits attention because iron deficiency (ID) during pregnancy is associa...
Higher concentrations of serum iron and transferrin saturation but not serum ferritin are associated with cancer outcomes
Busselton Health Study cancer outcomes follow-up study iron risk factors
2018/12/14
Background: Although the carcinogenic potential of iron has been shown, evidence from observational studies that have linked serum iron variables and cancer outcomes has been inconsistent.