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Biomarker identified for likely aggressive,early stage breast cancer
Biomarker likely aggressive early stage breast cancer
2017/4/27
The one-size-fits-all approach to early stage breast cancer creates a paradox: Millions of dollars are spent on unnecessary surgeries and radiation to treat women with low-risk ‘in situ’ lesions, an e...
Tasmanian devils are evolving in response to a highly lethal and contagious form of cancer, a Washington State University researcher has found.Andrew Storfer, WSU professor of biology, and an internat...
Two-way communication between cancer cells appears to be key to their becoming motile, clustering and spreading through metastasis, according to Rice University scientists.Members of Rice’s Cente...
MOLECULAR PROFILING IN BREAST CANCER AND TOXICOGENOMICS
molecular profiling,breast cancer toxicogenomics feature selection
2015/1/9
This dissertation presents a body of research that attempts to tackle the ‘overfitting’ problem for gene signature and biomarker development in two different aspects (mechanistically and computational...
Advancing Toxicology-Based Cancer Risk Assessment with Informatics
carcinogenecity informatics risk assessment
2015/1/9
Since exposure to carcinogens can occur in the environment from various point sources, cancer risk assessment attempts to define and limit potential exposure such that the risk of developing cancer is...
Safety and Efficacy of Laparoscopy-Assisted Gastrectomy after Endoscopic Submucosal Dissection for Early Gastric Cancer: A Retrospective Report
Early Gastric Cancer Laparoscopic Gastrectomy ESD
2013/1/30
Background: This study aimed to determine the safety and effectiveness of laparoscopy-assisted distal gastrectomy (LADG) after ESD. Methods: We reviewed patients with gastric cancer who underwent dist...
Lack of MICA Expression Predicts a Worse Prognosis in Patients with Bladder Cancer
Bladder Cancer NKG2D Ligands MICA Survival Prognosis
2013/1/31
Background: Bladder and lung cancer are among the ten most common cancers in both genders. The NKG2D receptor and one of its ligands, MICA, are associated with smoking and susceptibility to both chron...
Association between human glutathione S-transferase omega rs4925 polymorphism and bladder cancer
Bladder Cancer Cigarette Smoking GSTO1 Polymorphism
2013/1/28
Glutathione S-transferases (GSTs) play an important role in the detoxification of polycyclic aromatic hydrocarbons and aromatic amines, the toxic substances contained in cigarettes. GST Omega 1 (GSTO1...
Overcome the Impairment of NK Cells for Icon and Antibody Immunotherapy of Cancer
Natural Killer Cells Antibody Cancer Immunotherapy Icon Dietary Supplements
2013/1/30
Natural killer (NK) cells play an important role in innate immunity and in mediating antibody and Icon (an antibody-like factor VII/IgG1 Fc immunoconjugate, which, to our best knowledge, was the first...
OPRT Is a Potential Predictive Factor for the Response to S-1 in Gastric Cancer
S-1 Chemotherapy Gastric Cancer Orotate Phosphoribosyltransferase Biomarker
2013/1/30
Objective: To analyze the impact of mRNA expression of oral fluoropyrimidine (S-1) metabolism (thymidylate synthase, dihydropyrimidine dehydrogenase, thymidine phosphorylase, and orotate phosphoribosy...
Standard Prophylactic Strategy against Peritoneal Dissemination Metastasis in Gastric Cancer
Gastric Cancer Intra-Peritoneal Free Cancer Cells Peritoneal Metastasis EIPL
2013/1/30
Peritoneal carcinomatosis is the most frequent pattern of metastasis and recurrence in patients with gastric cancer, and the prognosis of those patients with peritoneal metastasis is extremely poor. O...
Endoscopic Staging and Treatment of Early Gastric Cancer
Early Gastric Cancer Endoscopic Mucosa Resection Endoscopic Submucosal Dissection Endoscopic
2013/1/30
Gastric cancer is the most common cancer worldwide and it is often diagnosed in an advanced stage. In countries where screening endoscopy is performed widely, early detection is possible. In fact, ear...
Loss of Heterozygosity (LOH) is commonly considered to be one of a reason when some genes lose their function. Numbers of tumor suppressor genes are existing on the LOH lesion and chromosome 16q24 had...
Reduction Mammaplasty as a Treatment Option for Early Breast Cancer
Breast Reduction Cancer Bilateral Mammaplasty Conservative
2013/1/30
Background: Although reduction mammaplasty is a well-known technique for cosmetic purposes, there are few previous reports regarding its application and clinical outcome following conservative breast ...
Cervical cancer screening among female undergraduates and staff in the Niger delta region of Nigeria
Knowledge Cervical Cancer Risk Factors Screening Niger Delta
2013/1/31
A significant decrease in the incidence of cervical cancer and mortality is expected when all eligible women have access to regular Screening tests. Factors that can influence participation rate inclu...