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Serum 25-hydroxyvitamin D and the risk of cardiovascular disease: dose-response meta-analysis of prospective studies
25-hydroxyvitamin D cardiovascular disease meta-analysis dose-response CVD mortality
2018/11/13
Background: During the past decade, an increasing number of prospective studies have focused on the association between vitamin D and cardiovascular disease (CVD). However, the evidence on the relatio...
Folic acid therapy reduces serum uric acid in hypertensive patients: a substudy of the China Stroke Primary Prevention Trial (CSPPT)
controlled hyperuricemia olic acid supplementation new-onset hyperuricemia total homocysteine uric acid concentrations
2018/11/13
Background: The effect of folic acid supplementation on uric acid (UA) concentrations is still inconclusive.
Serum potassium is a predictor of incident diabetes in African Americans with normal aldosterone: the Jackson Heart Study
potassium diabetes risk racial disparity in diabetes risk diabetes risk factor African Americans
2018/11/12
Background: Low-normal potassium is a risk factor for diabetes and may account for some of the racial disparity in diabetes risk. Aldosterone affects serum potassium and is associated with insulin res...
Effects of green tea catechin extract on serum lipids in postmenopausal women: a randomized, placebo-controlled clinical trial
green tea EGCG blood lipids postmenopausal cardiovascular randomized controlled trial
2018/12/19
Background: Green tea has been suggested to improve cardiovascular disease risk factors, including circulating lipid variables. However, current evidence is predominantly based on small, short-term ra...
Maternal serum retinol and β-carotene concentrations and neonatal bone mineralization: results from the Southampton Women’s Survey cohort
bone development epidemiology pregnancy vitamin A, retinol β-carotene
2018/12/14
Background: Studies in older adults and animals have suggested contrasting relations between bone health and different vitamin A compounds. To our knowledge, the associations between maternal vitamin ...
Maternal serum retinol and β-carotene concentrations and neonatal bone mineralization: results from the Southampton Women’s Survey cohort
bone development epidemiology pregnancy vitamin A retinol β-carotene
2018/12/18
Background: Studies in older adults and animals have suggested contrasting relations between bone health and different vitamin A compounds. To our knowledge, the associations between maternal vitamin ...
Prospective study of serum cysteine and cysteinylglycine and cancer of the head and neck, esophagus, and stomach in a cohort of male smokers
cysteine esophageal neoplasms head and neck neoplasms stomach neoplasms upper gastrointestinal tract cancers
2018/12/14
Background:The nonessential amino acid cysteine is known to be involved in many antioxidant and anticarcinogenic pathways. Cysteinylglycine is a pro-oxidant metabolite of glutathione and a precursor o...
Serum calcium and incident type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) study
calcium-sensing receptor polymorphism cohort study diabetes mellitus race serum calcium
2018/12/18
Background: Elevated serum calcium has been associated with a variety of metabolic abnormalities and may be associated with a greater risk of diabetes.
Higher concentrations of serum iron and transferrin saturation but not serum ferritin are associated with cancer outcomes
Busselton Health Study cancer outcomes follow-up study iron risk factors
2018/12/14
Background: Although the carcinogenic potential of iron has been shown, evidence from observational studies that have linked serum iron variables and cancer outcomes has been inconsistent.
Serum 25-hydroxyvitamin D concentration is inversely associated with mucosal inflammation in patients with ulcerative colitis
inflammatory bowel disease mucosal inflammation tight junction ulcerative colitis vitamin D
2018/12/3
Background: Vitamin D exerts anti-inflammatory actions both in vitro and in murine models of colitis. In previous studies, we demonstrated that vitamin D protects against the development of colitis by...
Elevations in serum anti-flagellin and anti-LPS Igs are related to growth faltering in young Tanzanian children
child growth environmental enteric dysfunction intestinal biomarkers anti-flagellin antibodies anti-LPS antibodies intestinal
2018/11/30
Background: Antibodies to LPS and flagellin have been described as indirect measures of increased gastrointestinal permeability and may be markers of environmental enteric dysfunction (EED), which is ...
Serum n–6 polyunsaturated fatty acids, Δ5- and Δ6-desaturase activities, and risk of incident type 2 diabetes in men: the Kuopio Ischaemic Heart Disease Risk Factor Study
polyunsaturated fatty acids desaturase enzymes serum zinc type 2 diabetes prospective study
2018/11/30
Background: The role of n–6 (ω-6) polyunsaturated fatty acids (PUFAs) in type 2 diabetes (T2D) is inconclusive. In addition, little is known about how factors involved in PUFA metabolism, such as zinc...
Relationship Between Serum Hepcidin and Ferritin Levels in Patients With Thalassemia Major and Intermedia in Southern Iran
Hepcidin Hydroxyurea Ferritin Thalassemia Intermedia Thalassemia Major
2015/11/9
Background: Hepcidin is a key regulator of iron absorption in humans. It is mainly affected by hypoxia and iron stores.
Serum Ferritin Levels Correlation With Heart and Liver MRI and LIC in Patients With Transfusion-Dependent Thalassemia
Beta-thalassemia Ferritin Magnetic Resonance Imaging Liver Heart
2015/10/22
Background: Iron-loaded cardiac complication is the essential cause of mortality in patients with thalassemia. Early detection and treatment of cardiac over-load can reduce mortality.
Comparison of the Effects of Eicosapentaenoic Acid With Docosahexaenoic Acid on the Level of Serum Lipoproteins in Helicobacter pylori:A Randomized Clinical Trial
Helicobacter pylori Eicosapentaenoic Acid Docosahexaenoic Acid Cholesterol Triglyceride
2015/10/16
Background: Helicobacter pylori infection is the most common chronic bacterial infection around the world and an important cause of gastrointestinal disorders, which might be involved in the pathogene...