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Expression of the Recombinant Major Allergen of Salsola kali Pollen (Sal k 1) and Comparison with Its Low-Immunoglobulin E-Binding Mutant
comparison expression mutant Sal k 1 Salsola kali
2010/11/12
Background: The inhalation of Salsola kali pollen is an important cause of pollinosis during summer and early fall throughout desert and semi-desert areas. Sal k 1 has been previously reported as a ma...
Local Induction of a Specific Th1 Immune Response by Allergen Linked Immunostimulatory DNA in the Nasal Explants of Ragweed-Allergic Subjects
allergen allergic rhinitis CpG motif immunotherapy vaccination
2010/11/16
RW or Amb-a-1 increased the number of IL-4, IL-5, and IL-13 mRNA+ cells in the tissue compared to medium alone. AIC had similar cytokine mRNA reactivity as control tissue. AIC and TT increased IFNγ-mR...
Cloning and Expression of the Allergen Cro s 2 Profilin from Saffron (Crocus sativus)
allergy cloning Cro s 2 profilin recombinant allergen saffron
2010/11/16
Background: Profilin is a panallergen that is recognized by IgE in allergic patients. Allergy to saffron (Crocus sativus) pollen has been described in people exposed to its pollen. Saffron contains a ...
Allergen-specific T-cell Response in Patients with Phenytoin Hypersensitivity; Simultaneous Analysis of Proliferation and Cytokine Production by Carboxyfluorescein Succinimidyl Ester (CFSE) Dilution Assay
allergen-specific T cell CFSE dilution assay IFN-γ lymphocyte transformation test phenytoin hypersensitivity
2010/11/18
Phenytoin-specific proliferation may be detected with greater sensitivity by the CFSE dilution assay than the conventional LTT. The assay revealed that both CD4+ and CD4- T cells proliferated and prod...
Immunologic determination of the major allergen, Cry j 1, in Cryptomeria japonica pollen of 117 clones in Toyama prefecture: Some implications for further forestry research in pollinosis prevention
Cry j 1 Cryptomeria japonica D. Don environmental factor genotype variation Japanese cedar pollinosis
2010/11/24
Background: A number of recent studies have clarified the characteristics of major allergens of Cryptomeria japonica, such as the locality, molecular weights of Cry j 1 and Cry j 2 and cross-reactivit...
Future of allergen-specific immunotherapy.