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Protection of pulmonary epithelial cells from oxidative stress by hMYH adenine glycosylase
oxygen toxicity hMYH adenine glycosylase
2014/12/12
Background: Oxygen toxicity is a major cause of lung injury. The base excision repair pathway is one of the most important cellular protection mechanisms that responds to oxidative DNA damage. Lesion-...
Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress; Use of APE1 small molecule inhibitors to delineate APE1 functions
base excision repair APE1/Ref-1 oxidative stress
2014/12/12
Oxidative DNA damage has been implicated in a number of central nervous system pathologies. The base excision repair (BER) pathway is one of the most important cellular protection mechanisms that resp...
Enhanced mtDNA repair and cellular survival following oxidative stress by targeting the hOGG repair enzyme to mitochondria
DNA repair DNA damage
2014/12/12
Oxidative damage to mtDNA has been implicated as a causative factor in many disease processes and in aging. We have recently discovered that different cell types vary in their capacity to repair this ...
Yeast apurinic/apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress
DNA repair gene therapy
2014/12/12
Reactive oxygen species (ROS) have been implicated as one of the agents responsible for many neurodegenerative diseases. A critical target for ROS is DNA. Most oxidative stress-induced DNA damage in t...
The Effect of Maternal Selenium Supplementation on Pregnancy Outcome and the Level of Oxidative Stress in Neonates
Selenium Prooxidant-Antioxidant balance Neonate Complication Pregnancy
2015/9/21
Background: Pregnancy is regarded as a condition which is usually accompanied by oxidative stress. This study was undertaken to investigate the effect of maternal selenium supplementation during gesta...