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Allergen immunotherapy targets Th2 cells activated by specific allergens, which constitutes the basis of allergic disease. Therefore, this approach has therapeutic potential for a variety of allergic ...
Background: Natural rubber latex (NRL) allergy is a common occupational disease in health care workers (HCW). However, few reports have compared the major allergen of HCWs to those in gloves that are ...
Preadministration of antihistamine eye drops suppressed the symptoms induced by the allergen, which suggests that this is an effective early therapy for Japanese cedar pollinosis, if it is started bef...
The mean itching score in the levocabastine-treated group was 0.08 ± 0.06, which was significantly lower than the mean score of 1.98 ± 0.16 in the vehicle group (P < 0.0001). The redness and chemosis...
LTB4, a proinflammatory lipid mediator generated from arachidonic acid through the action of 5-lipoxygenase, has been known for over two decades and is implicated in a wide variety of inflammatory dis...
The role of interleukin (IL)-4 in the development of allergen-induced airway inflammation and bronchial hyperresponsiveness (BHR) is still controversial. To investigate the role of IL-4 in the develop...
The red soft coral that is found around the spiny lobster represents a major allergen and many fishermen, especially those that catch the spiny lobster, suffer from allergic symptoms. Therefore, in th...
Allergen-specific immunotherapy (SIT) involves the administration of gradually increasing amounts of an allergen extract to reduce clinical symptoms of allergy. Well-controlled clinical trials have de...
Background: Hypersensitivity to the group 1 grass pollen allergens is a significant causative factor in the onset of symptoms for hay fever sufferers. To better understand the IgE reactivity of the gr...
Background: We developed an in vitro system to diagnose allergy using an allergen microarray and photo-immobilization technique. Photo-immobilization is useful for preparing the allergen microarray be...
We used flow cytometry to investigate the expression of α4β7 integrin on peripheral blood CD4+ T cells stimulated with αs-casein, one of the major allergens in milk allergy, in patients with milk-indu...

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