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上调miR-181a抑制香烟提取物诱导的支气管上皮细胞致炎因子生成与collagen IV、fibronectin和α-SMA表达
微小RNA-181a 慢性阻塞性肺疾病 气道炎症 气道重塑 NF-κB/TGF-β1/Smad3信号通路
2020/9/11
探讨微小RNA-181a（miR-181a）对香烟提取物（cigarette smoke extract，CSE）诱导的人支气管上皮细胞（human bronchial epithelial cells， HBECs）致炎因子生成与IV型胶原蛋白（collagen IV）、纤连蛋白（fibronectin）和α-平滑肌肌动蛋白（α-SMA）表达的影响，并分析其可能的机制。方法：RT-qPCR检测C...
Undenatured type II collagen (UC-II®) for joint support:a randomized,double-blind,placebo-controlled study in healthy volunteers
UC-II Undenatured type II collagen Joint function Knee extension Stepmill Joint pain
2015/7/28
UC-II contains a patented form of undenatured type II collagen derived from chicken sternum. Previous preclinical and clinical studies support the safety and efficacy of UC-II in modulating joint disc...
Reactivity of IgE in fish-allergic patients to fish muscle collagen
allergen collagen fish muscle parvalbumin
2010/11/24
When 15 sera from fish-allergic patients were subjected to ELISA using bigeye tuna collagen and parvalbumin, 10 sera reacted only to parvalbumin, two reacted only to collagen, two reacted to both coll...
Pulmonary involvements caused by changes in peripheral perfusion in collagen-vascular diseases
collagen-vascular diseases diffusion capacity (DLco) drug-induced perfusion pulmonary hypertension pulmonary involvement vasculopathy
2010/11/22
Collagen-vascular diseases (CVD) involve many organs. Among organ involvements, pulmonary disorders may determine the prognosis of CVD. Because the vasculature and blood perfusion are commonly altered...