搜索结果: 31-45 共查到“国际动态 药物化学”相关记录90条 . 查询时间(1.885 秒)
美国利用金属简化抗体药物合成
美国 金属简化 抗体药物 药物合成
2017/10/17
美国莱斯大学科学家开发出一种“通用盒”以简化癌症药物设计，这种方法能够对将药物运送到靶细胞的天然抗体进行修饰，其关键在于添加金属元素。研究人员发现稀有过渡金属铑可以作为设计和制备抗体药物共轭物的有效元素，而抗体药物共轭物已成为靶向给药的标准工具，用于化学治疗剂等多个方面。他们开发出一种类似酶的多金属蛋白质，用于催化多种抗体。这一简单过程将帮助实验室人员测试各种抗体来源和抗原靶标的相对功能，以筛选出...
Chemists use electricity to amp up drug manufacturing（图）
Chemists electricity drug manufacturing
2017/9/5
Give your medicine a jolt. By using a technique that combines electricity and chemistry, future pharmaceuticals – including many of the top prescribed medications in the United States – soon may be ea...
Scientists Enlist Baker’s Yeast to Find New Medicines
Scientists Enlist Baker’s Yeast New Medicines
2017/9/1
One of the hardest parts in drug discovery is pinning down how a medicine actually works in the body. It took nearly 100 years to uncover the molecular target of aspirin, but even with cutting-edge te...
Rice scientists simplify the incorporation of nitrogen into molecules
Rice scientists simplify the incorporation nitrogen into molecules
2017/7/24
A Rice University laboratory that specializes in synthesizing reagents and intermediate molecules for the design and manufacture of drugs and other fine chemicals has delivered on a promise ...
Greener molecular intermediates may aid drug design
Greener molecular intermediates drug design
2017/7/24
Scientists at Rice University have simplified their approach to synthesize a highly versatile family of precursors en route to biologically active compounds. Their method should make drug design and d...
Micron-sized hydrogel cubes show highly efficient delivery of a potent anti-cancer drug
Micron-sized hydrogel cubes highly efficient delivery anti-cancer drug
2017/7/24
Many potent anti-cancer drugs have major drawbacks — they fail to mix with water, which means they will have a limited solubility in blood, and they lack selectivity to cancer cells.Researchers at the...
Figuring Out the 3D Shape of Molecules with a Push of a Button
3D Shape a Push of a Button
2017/7/21
A team of researchers led by Carnegie Mellon University chemist Roberto R. Gil and Universidade Federal de Pernambuco chemist Armando Navarro-Vázquez has developed a program that automates the process...
X-Ray Study Reveals Long-Sought Insights Into Potential Drug Target
X-Ray Long-Sought Insights Potential Drug Target
2017/4/27
X-ray studies done in part at the Department of Energy’s SLAC National Accelerator Laboratory have produced surprising insights into the workings of a hormone receptor associated with blood pressure r...
UAB creates triple-threat cancer-fighting polymer capsules for guided drug delivery
UAB triple-threat cancer-fighting polymer capsules drug delivery
2017/4/27
Chemists at the University of Alabama at Birmingham have designed triple-threat cancer-fighting polymer capsules that bring the promise of guided drug delivery closer to preclinical testing....
对于抗菌素滥用导致的具有抗药性的高致病性细菌，目前还没有疫苗或良药应对。不过，这种状况有望因以色列研究人员的“突破性”发现而改变。他们找到了超级病菌耐甲氧西林金黄色葡萄球菌攻击人体的“弹药”，新研究成果将有助于研发具有新颖作用机制的抗菌素应对超级病菌。以色列理工学院生物学副教授梅塔尔·兰多和同事在新出版的《科学》杂志上介绍，她们通过研究首次发现存在着一种独特的类淀粉蛋白PSMα3，耐甲氧西林金黄色...
英国成立药物发现弹射创新中心
新药品 新服务
2017/2/15
英国在位于英格兰西北地区的阿尔德利园区新近成立了药物发现弹射创新中心，依托北方经济动力区良好的科学与创新基础，重点支持企业开发药物临床前评价新技术。药物发现弹射创新中心的目标是加强英国商业化的临床能力，以提高药品的开发和生产能力，使之成为推出新药品和新服务的世界领先之地。
便宜铁盐催化可生成药用关键结构
便宜铁盐 药用关键结构
2017/2/15
英国哈斯德菲尔德大学科学家首次证实，普通铁盐可取代贵重的稀有金属用作催化剂，产生一种全新的化学反应类型，可催化生成生物活性天然产品中常见的螺环状杂环结构框架，且成本降低了1000倍。该研究发表在《自然·化学》杂志上，其中的核心反应部分已获专利审批。
IUPUI chemists develop new technique that could speed drug development
IUPUI chemists new technique speed drug development
2016/12/13
Synthesizing useful new compounds is what pharmaceutical discovery and development is all about. Researchers at the School of Science at Indiana University-Purdue University Indianapolis have devised ...
Chemistry method expedites path to useful molecules for medicine
Chemistry method expedites path molecules for medicine
2016/9/12
Opening a broad vista in the search for effective pharmaceuticals, a collaboration of Chinese and U.S. chemists has laid out a highly efficient new method to convert abundant organic molecules into ne...