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反义药物在经历了20年后,又迎来了一个蓬勃的发展阶段。研究结果表明,反义药物在抗肿瘤、抗炎和抗病毒等方面展现出令人鼓舞的前景,反义寡核苷酸可能成为新药开发新的生长点。本文调查了近年反义寡核苷酸药代动力学的研究进展,对反义寡核苷酸的吸收、分布、代谢和排泄进行了详细的综述。
Objectives. To compare 2006–2007 and projected 2010–2011 advanced pharmacy practice experience (APPE) availability and needs for 4 colleges and schools of pharmacy in Georgia and Alabama and to examin...
Objectives. To identify problems that pharmacy practice faculty members face in pursuing scholarship and to develop and recommend solutions. Methods. Department chairs were asked to forward a Web-bas...
葡萄球菌(主要是金黄色葡萄球菌,简称金葡萄、表皮葡萄球菌)是我院临床标本分离细菌中的主要病原菌,也是近年来引起医院内感染的主要细菌。耐甲氧西林葡萄球菌(methicillin-resistant Staphylococcus, MRS)有很高的耐药率和多重耐药性,给临床治疗带来相当大的困难。因此,及时了解与分析它对常用抗生素的耐药情况,可为临床选择用药提供参考。
介绍一个药学研究中数据处理的实用软件。方法举例论述DPS数据处理系统在药学研究中的实际应用。结果方法简便、实用、迅速、准确,能显著提高工作效率。结论DPS数据处理系统是一个优秀软件,应推广应用。
健康报2007年5月29日报道,全球范围进行的ONTARGET研究进入尾声。该项目是迄今为止全球规模最大、历时最长的心血管系统保护研究,也是第一个研究ARB(美卡素)和ACEI(雷米普利)单独或联合应用预防心血管疾病和死亡方面的影响的项目。41个国家的31000多名心血管疾病高危患者入选该项研究,每个病人随访长达5.5年。此项研究包括两个平行试验:主要试验为持续单独使用美卡素及美卡素与ACEI联合...
Surveys are perhaps the most used, and sometimes misused, methodological tool among academic researchers. Self-administered survey questionnaires (and guided interviews) allow us to elicit behaviors, ...
Objectives. This article describes a class project utilizing an electronic-based format, entitled “VITAL: a virtual interactive case tool for asynchronous learning.” The objective was to encourage sel...
Current practices used to teach the medication history interview to Doctor of Pharmacy students were examined. An online survey was emailed to curriculum committee chairpersons at all 91 schools of ph...
Senior advanced practice experience assignments are made for the entire academic year using a computer based selection process. Each year the academic programs section staff of the department of pharm...
Pharmacy education in the United States is currently in a state of transition as the nation's schools of pharmacy move from the five-year Bachelor of Science degree to the Doctor of Pharmacy degree. A...
Increasing complexity of medical studies and statistics make it important for pharmacists to be able to evaluate the appropriateness of statistical tests used in the literature and assess if reasonabl...
介绍了一种用优选法处理倒数升温和对数升温,用优选法和辛普森积分法处理线性升温加速试验数据的新算法;讨论了常规算法的缺点;比较了3种程序升温方法的优缺点。结果表明,在本文所介绍的新算法中,没有作任何近似处理,克服了常规算法的缺点。在上述3种程序升温方法中,以倒数升温最好,线性升温次之,对数升温较差。

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