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Dissecting the expression landscape of RNA-binding proteins in human cancers
RNA-binding proteins cancer pathogenesis
2015/3/5
Background RNA-binding proteins (RBPs) play important roles in cellular homeostasis by controlling gene expression at the post-transcriptional level. Results We explore the expression of more than 800...
Expression and Activities of Matrix Metalloproteinases under Oscillatory Shear in IL-1-Stimulated Synovial Cells
Expression Matrix Metalloproteinases
2014/11/13
Matrix metalloproteinases (MMPs) are known to play a critical role in tissue disintegration, and an elevated level of MMPs is observed in synovium and synovial fluid of joints with rheumatoid arthriti...
Physical Weight Loading Induces Expression of Tryptophan Hydroxylase 2 in the Brain Stem
mechanical loading serotonin
2014/11/6
Sustaining brain serotonin is essential in mental health. Physical activities can attenuate mental problems by enhancing serotonin signaling. However, such activity is not always possible in disabled ...
Lack of MICA Expression Predicts a Worse Prognosis in Patients with Bladder Cancer
Bladder Cancer NKG2D Ligands MICA Survival Prognosis
2013/1/31
Background: Bladder and lung cancer are among the ten most common cancers in both genders. The NKG2D receptor and one of its ligands, MICA, are associated with smoking and susceptibility to both chron...
Transcriptional Expression Profile of Toll Like Receptor 1 - 10 mRNA in Bovine Peripheral Mononuclear Cells in Response to Foot and Mouth Disease Antigens
Innate Immunity FMDV DNA Vaccine TLR Genes
2013/1/28
Toll like receptors are the primary component of innate immune response. The comparison of expression of innate immune genes TLR 1 - 10 was carried out by real time PCR by quantifying mRNA in bovine P...
In vivo effect of 17-β-estradiol, progesterone, hCG and expression of P53 and P21 in endometrial Ishikawa cells
Ishikawa cells 17-β-estradiol Progesterone hCG P53 P21 Endometrium
2013/1/31
Purpose: The study examined the effect of 17-β-estradiol, progesterone and hCG on cell proliferation and the effect of cell cycles regulating P53 and P21 protein on expression levels of Ishikawa endom...
Loss of Heterozygosity (LOH) is commonly considered to be one of a reason when some genes lose their function. Numbers of tumor suppressor genes are existing on the LOH lesion and chromosome 16q24 had...
The Influence of Survival Analysis on Runx3 Gene Expression in the Primary Tumor of Patients Suffering from Stomach Carcinoma
Stomach Neoplasms Runx3 Prognosis
2013/1/29
Background: Runt domain transcription factor 3 (Runx3) is a putative tumor suppressor in human neoplasia. Previous researches suggested that a lack of Runx3 function contributed to human gastric carci...
SAP Expression in Candida albicans Strains Isolated from Mexican Patients with Vaginal Candidosis
Candida albicans RHVE SAP Expression
2013/1/29
To determine the frequency and expression of the ten SAP (secreted aspartyl protease) genes in a group of Candida albicans strains isolated from Mexican women suffering from vaginal candidosis, a grou...
Flavin-Containing Monooxygenase (FMO) Protein Expression and Its Activity in Rat Brain Microvascular Endothelial Cells
Rat Microvascular Endothelial Cells Flavin-Containing Monooxygenase (FMO)
2013/2/19
The aim of this study was to examine whether flavin-containing monooxygenase (FMO) protein was expressed in cultured rat brain microvascular endothelial cells (BMECs), which constitute the blood-brain...
Molecular Analyses of Early-Onset Gastric Cancer in Brazilian Patients: TP53 Mutations, Cadherin-Catenin and Mucins Proteins Expression
Early-Onset Gastric Cancer Young Patients Cellular Adhesion TP53 Mutations
2013/1/29
Early gastric carcinomas may develop with a molecular profile differing from sporadic carcinomas occurring at a later age. In this study, we analyzed a retrospective series of 88 patients with gastric...
Effectiveness of sub-maximal intermittent exercise on muscle glycogen depletion, PGC-1α and PDK-4 gene expression
ntermittent Exercise Muscle Glycogen Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α
2013/1/30
Several metabolic gene expressions are regulated in concert with muscle glycogen status. We hypothesized that intermittent exercise performed at high but sub-maximal intensities with long recovery per...
5-HTr Expression in Primary Trigeminal Neuron Following Injury
Sensory Neurons Plasticity Trigeminal Ganglia Neurons
2013/1/29
Trigeminal ganglia neurons significantly affect the amplitude and type of 5-HT receptor gene expression following activation of their axon terminals and sensitisation by painful stimuli. Moreover, the...
Imaging C-Fos Gene Expression in Burns Using Lipid Coated Spion Nanoparticles
Positive Contrast Transverse Relaxation in the Rotating Frame (T2r)
2013/1/29
MR imaging of gene transcription is important as it should enable the non-invasive detection of mRNA alterations in disease. A range of MRI methods have been proposed for in vivo molecular imaging of ...
Influence of nanofibers on growth and gene expression of human tendon derived fibroblasts
nanofibers growth and gene expression human tendon fibroblasts
2010/2/25
This study indicates that the use of nanofibers influence expression of genes associated with the extra cellular matrix formation. The composition of the nanofibers plays a critical role. While PLLA/C...