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Influence of β - cyclodextrin complexation on lovastatin release from osmotic pump tablets (OPT)
β-Cyclodextrin Inclusion complex Elementary osmotic pump (EOP)
2010/4/8
An extended-release osmotic dosage form was designed and the effect of β-cyclodextrin (BCD) inclusion complexation on the solubility of lovastatin in aqueous media was investigated. The lovastatin BCD...