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Role of a Th2 cytokine inhibitor in asthma treatment
cough variant asthma eosinophilic airway inflammation interleukin-4 interleukin-5 interleukin-13 steroid-sparing effect
2010/11/22
The airway wall of asthmatic patients is infiltrated with inflammatory cells, consisting chiefly of eosinophils and T lymphocytes. Among these T lymphocytes, Th2 cells are involved in the regulation o...
Adjuvants that Enhance Th2 or Tr Responses
adjuvants allergy dendritic cells HLA Notch ligands Th2 toll-like receptors
2010/11/22
It is well-known that many isoforms of toll-like receptors (TLRs) function as Th1 adjuvant receptors. Thus, the ligands induce Th1 differentiation in an antigen non-specific manner. During the past fe...