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探讨大鼠分泌性中耳炎中耳微环境中的Th2/Th1细胞失衡模式。方法 选用SD大鼠20只，随机分为实验组和对照组，每组各10只(20耳)。实验组以卵清蛋白腹腔致敏后耳内激发制成分泌性中耳炎(OME)模型，对照组以PBS替代卵清蛋白。耳内激发后2 d处死动物，采用HE染色切片观察各组中耳黏膜病理变化及炎症细胞的改变，采用ELISA法测定各组大鼠中耳腔灌洗液中Th2型细胞因子白介素4(IL-4)和Th1...
Th1, Th2, Tc1 and Tc2 cells of patients with otolaryngological diseases
acute sensorineural hearing loss Kimura's disease Meniere's disease Tc1 Tc2 Th1 Th2 Wegener's granulomatosis
2010/11/22
Cytokines are important regulatory mediators secreted by T cells and other immunoactive cells. Based on the cytokine synthesis patterns, CD4 T cells can often be classified into at least two populatio...