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Resolving a 40-year old dilemma to improve the treatment of nerve pain（图）
a 40-year old dilemma nerve pain
2010/10/13
Dr Michel Coppieters' research into the unexplained world of nerve pain aims to contribute to improved treatment and prevention of this mystifying and increasingly common condition.
Dr Coppieters ha...
A Prospective Survey on Safety of Sustained-Release Theophylline in Treatment of Asthma and COPD
adverse drug reactions asthma COPD safety evaluation sustained-release theophylline
2010/11/19
3,921 patients were included in the safety evaluation. No serious adverse reactions were observed among the patients in this survey, although 54 patients (1.38%) exhibited non-serious adverse reaction...
Possibility of lipid microsphere-encapsulated Y-24180 as an injectable drug and an inhaler for the treatment of bronchoconstriction
bronchoconstriction inhaler intravenous treatment lipid microspheres platelet-activating factor antagonist Y-24180
2010/11/25
Y-24180 ((±)-4-(2-chloro-phenyl)-2-[2-(4-isobuthylphenyl)ethyl]-6,9-dimethyl-6H-thieno[3,2f][1,2,4]triazolo[4,3-a)[1,4]diazepine) is a lipophilic platelet- activating factor (PAF) antagonist. In the p...
Once-daily use of inhaled corticosteroids: A new regimen in the treatment of persistent asthma
asthma budesonide inhaled corticosteroids once daily Pulmicort Respules® Pulmicort Turbuhaler®
2010/11/25
Asthma is a disease of chronic airway inflammation that is characterized clinically by bronchial hyperresponsiveness and airflow limitation. Chronic inflam- mation, coupled with ongoing repair of airw...
Cytokine and anti-cytokine therapy for the treatment of asthma and allergic disease
anti-interleukin-4 anti-interleukin-5 anti-tumor necrosis factor-α asthma cytokines
2010/11/22
Asthma is a chronic inflammatory disorder of the airways superimposed upon structural changes that include an increase in smooth muscle and airway wall remodeling. In addition to a background of chron...
Efficacy and safety of methylxanthines in the treatment of asthma
adverse effects asthma efficacy methylxanthines theophylline
2010/11/22
Theophylline is a bronchodilator that also has an anti-inflammatory effect. In Japan, methylxanthines, including theophylline and aminophylline (theophylline ethylenediamine), have been used widely in...
A Study of the Usefulness of Anti-inflammatory Treatment for Mild Intermittent Asthma (Step 1): Budesonide vs. Montelukast
airway hyperresponsiveness airway inflammation anti-inflammatory treatment early intervention exhaled nitric oxide induced sputum mild intermittent asthma
2010/11/19
Anti-inflammatory treatment is necessary even for mild intermittent asthma (step 1). We believe that early intervention with anti-inflammatory drugs is important for the prevention of airway remodelin...