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Background: Nowadays the importance of oral health to life quality is not obvious to anyone in our world. Oral lesions can interfere with daily social activities in involved patients through impacts o...
Oral bioavailability and intestinal disposition of dehydroandrographolide in rats
脱水穿心莲内酯 药代动力学 肠道处置 Caco-2细胞 大鼠在体肠灌流
2012/8/20
目的研究脱水穿心莲内酯在大鼠体内的口服生物利用度和肠道处置，为其在临床的使用和开发提供有用的信息。方法研究脱水穿心莲内酯在大鼠体内的药代动力学行为。采用Caco-2细胞模型和大鼠在体肠灌流模型研究脱水穿心莲内酯在大鼠体内的肠道处置。结果脱水穿心莲内酯的口服绝对生物利用度是11.92%。在Caco-2细胞模型中，脱水穿心莲内酯从基底膜到顶端膜方向转运的表观渗透系数（5.37×10-5 cm/s）约等...
Comparison of Oral and Intravenous Proton Pump Inhibitor on Patients with High Risk Bleeding Peptic Ulcers: A Prospective, Randomized, Controlled Clinical Trial
Proton pump inhibitor Bleeding Peptic ulce
2015/9/23
Background: Proton pump inhibitors (PPIs) decrease the rate of rebleeding following endoscopic hemostatic therapy in patients with bleeding peptic ulcers. This study compares the efficacy of oral omep...
Rush Specific Oral Tolerance Induction in School-Age Children with Severe Egg Allergy: One Year Follow Up
egg allergy food allergy immunotherapy oral tolerance rush
2010/11/12
Background: At present, the only treatment for food allergy is to avoid the allergy-causing food. Some trials of specific oral tolerance induction (SOTI) have been carried out, but the rate of toleran...
PHARMACOKINETIC COMPARISON BETWEEN REGULAR INSULIN AND ORAL INSULIN BASED ON SUPERPOROUS HYDROGEL POLYMERS IN HEALTHY VOLUNTEERS
C–peptide Oral insulin SPH SPHC
2009/12/30
Background: All contemporary methods of insulin administration are non-physiological. Insulin is not absorbed from the gastrointestinal tract because of its peptide nature. The aim of the present stud...
Diagnosis of Food Allergy Based on Oral Food Challenge Test
food hypersensitivity guideline immunoglobulin E oral food challenge tolerance
2010/11/16
Diagnosis of food allergy should be based on the observation of allergic symptoms after intake of the suspected food. The oral food challenge test (OFC) is the most reliable clinical procedure for dia...
Bioprosthetic Heart Valve Replacement: Oral Anticoagulation or Antiplatelet Therapy?A Still Active Controversy
Bioprosthetic Heart Valve Replacement:Oral Anticoagulation Antiplatelet Therapy
2009/12/7
Bioprosthetic Heart Valve Replacement: Oral Anticoagulation or Antiplatelet Therapy? A Still Active Controversy。
Effects of Oral L-Glutamine,Insulin and Laxative on the Severity of Acute Pancreatitis
Department of First Surgery, Ankara Numune Training and Research Hospital Ankara,Konya-TURKEY Department of General Surgery,Selç uk University,Faculty of Medicine,Konya-TURKEY
2009/6/29
Aim: To investigate the effects of oral L-glutamine, insulin and laxative on the severity of acute pancreatitis. Materials and Methods: Forty adult male Sprague-Dawley rats were divided into 4 groups....
Effects of Oral Granisetron Treatment on Uremic Pruritus
Renal failure pruritus granisetron histamine serotonin
2009/6/23
The present study aimed to investigate the efficacy, safety, and tolerability of orally administered granisetron, a 5-HT3 receptor antagonist, and its possible effect on serum histamine and serotonin ...
A Comparative Efficacy of Oral Prednisone with Intramuscular Triamcinolone in Acute Exacerbation of Asthma
Asthma Prednisone Triamcinolone
2010/2/8
Corticosteroids are recommended for emergency management of an asthmatic attack. This study was designed to compare the effectiveness of oral and intramuscular steroid on spirometric results in acute ...
Effect of an oral β2-adrenoceptor agonist in a patient with idiopathic interstitial pneumonia
bronchial hypersensitivity dry cough KL-6 lung function test methacholine smooth muscle
2010/11/25
A 63-year-old man was referred to our hospital because of a dry cough. His chest roentgenogram revealed ground-glass opacities and honeycomb formations bilaterally in the lower lung fields. Pulmonary ...
Churg Strauss Syndrome after Introducing Oral Steroid to Inhaler - A Report of Three Cases
Churg Strauss Syndrome Corticosteroids Vasculitis
2010/2/8
The tetrad of bronchial asthma, severe sinusitis, nasal polyp, eosinophilia, and systemic vasculitis is the main feature of allergic granulomatosis and angitis (Churg- Strauss Syndrome). This vasculit...
Oral Fluid Antibody Detection in the Diagnosis of Gastric Helicobacter pylori Infection
Antibodies Enzyme-Linked Immunosorbant Assay Helicobacter pylori
2010/2/8
The aim of this study was to evaluate an enzyme - linked immunosorbent assay (ELISA) for the detection of anti - helicobacter pylori (H. pylori) specific IgG antibodies in specimens of oral fluid.
Al...