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Association of Variable Number of Tandem Repeats in Endothelial Nitric Oxide Synthase Gene with Coronary Artery Disease
Coronary artery disease Nitric oxide synthase gene Polymorphism
2010/2/3
Endo-derived nitric oxide (NO) is synthesized from L-arginine by endothelium nitric oxide synthase (eNOS). Since reduced NO synthesis has been implicated in the development of coronary atherosclerosis...
Role of nitric oxide in airway inflammation and hyperresponsiveness in bronchial asthma
arginine epithelial cells inhibitory nonadrenergic non-cholinergic nerve L-NAME peroxynitrate
2010/11/26
Nitric oxide (NO) is produced within the airways and has a variety of actions on the airway function. Nitric oxide is a potent bronchodilator, and NO released from airway epithelial cells and inhibito...
Induction of inducible nitric oxide synthase mRNA expression and nitric oxide production from macrophages stimulated with high-molecular size mite antigen HM1
airway inflammation high-molecular size mite antigen HM1 inducible nitric oxide synthase nitric oxide
2010/11/24
Gene expression of TNF-α, IL-12 p40 and iNOS was observed with HM1 stimulation of splenic macrophages from non-immunized mice. In addition, the release of NO induced by HM1-stimulated splenic macropha...
Increase of Exhaled Nitric Oxide (eNO) after Methylene Diphenyl Diisocyanate (MDI) Exposure in Isocyanate Workers with Bronchial Hyperresponsiveness
challenge test inhalation challenge isocyanates occupational asthma
2010/11/19
Fourteen of 22 symptomatic isocyanate workers showed BHR and five of these 14 developed an asthmatic response upon challenge with methylene diphenyl diisocyanate (MDI). In comparison with the group wi...