搜索结果: 31-45 共查到“知识库 变态反应学”相关记录53条 . 查询时间(3.43 秒)
Allergen immunotherapy: Current and new therapeutic strategies
allergen IgE immunotherapy T cell
2010/11/24
Allergen-specific immunotherapy (SIT) involves the administration of gradually increasing amounts of an allergen extract to reduce clinical symptoms of allergy. Well-controlled clinical trials have de...
Risk factors for asthma and allergic diseases among 13-14-year-old schoolchildren in Japan
allergy asthma childhood International Study of Asthma and Allergies in Childhood prevalence risk factor
2010/11/24
In analyses of family histories, the odds ratios (OR) of children who have a family history with no symptoms were significantly lower by risk factor-based analyses compared with those children with a ...
Self-reported hypersensitivity to exotic fruit in birch pollen-allergic patients
allergy birch pollen exotic fruit food hypersensitivity pollen-related food
2010/11/24
Background: The majority of Swedish birch pollen (BP)-allergic patients report hypersensitivity to some fruits, nuts and vegetables. Some BP-allergic patients complain 'I can't tolerate any fruit'. Th...
Effect of cysteine mutagenesis on human IgE reactivity of recombinant forms of the major rye grass pollen allergen Lol p 1
allergy grass pollen Lol p 1 mutagenesis rye grass
2010/11/24
Background: Hypersensitivity to the group 1 grass pollen allergens is a significant causative factor in the onset of symptoms for hay fever sufferers. To better understand the IgE reactivity of the gr...
Reactivity of IgE in fish-allergic patients to fish muscle collagen
allergen collagen fish muscle parvalbumin
2010/11/24
When 15 sera from fish-allergic patients were subjected to ELISA using bigeye tuna collagen and parvalbumin, 10 sera reacted only to parvalbumin, two reacted only to collagen, two reacted to both coll...
Induction of inducible nitric oxide synthase mRNA expression and nitric oxide production from macrophages stimulated with high-molecular size mite antigen HM1
airway inflammation high-molecular size mite antigen HM1 inducible nitric oxide synthase nitric oxide
2010/11/24
Gene expression of TNF-α, IL-12 p40 and iNOS was observed with HM1 stimulation of splenic macrophages from non-immunized mice. In addition, the release of NO induced by HM1-stimulated splenic macropha...
Possibility of non-steroidal treatment in allergic conjunctival diseases
allergic conjunctival disease corticosteroid immunosuppressive agent non-steroidal anti-inflammatory drug vernal keratoconjunctivitis
2010/11/22
In a recent epidemiological study, 15-20% of the population in Japan was estimated to have allergic conjunctivitis. Allergic conjunctival diseases (ACD) have a wide spectrum of clinical severity and t...
Role of dendritic cells in Th1/Th2 balance: A novel therapeutic target of allergic diseases
dendritic cell monocyte chemotactic protein-1 OX40 ligand regulatory T cells Th2
2010/11/22
Considerable evidence supports the role of dendritic cells (DC) in the pathogenesis of allergic diseases. Dendritic cells, as the most potent antigen-presenting cells (APC) for the induction of primar...
A Photo-immobilized Allergen Microarray for Screening of Allergen-specific IgE
allergen microarray allergen-specific IgE allergy diagnosis chemiluminescence photo-immobilization
2010/11/22
Background: We developed an in vitro system to diagnose allergy using an allergen microarray and photo-immobilization technique. Photo-immobilization is useful for preparing the allergen microarray be...
Subcutaneous Vaccination of Mycobacterium bovis Bacillus Calmette-Guérin Attenuates Allergic Inflammation in a Murine Model of Asthma
asthma CD4+ T cell chemokine Mycobacterium bovis Th1/Th2
2010/11/22
We found that BCG-vaccinated mice had fewer eosinophils in BALF and less severe allergic inflammation. The expression of IL-4 as well as Eotaxin and TARC was down-regulated in the vaccinated mice, whi...
Effects of Probiotics on the Immune System and Allergic Diseases
adaptive immunity allergic diseases commensals epithelial cells innate immunity intestinal microbiota probiotics
2010/11/22
Intestinal microbiota play a crucial role in the development of mucosal tolerance and adaptation. Perturbations in microbiota composition are strongly associated with allergies and asthma in westerniz...
Recent Developments in Genetic Study of Allergic Disease in the Japanese Population
allergic disease asthma atopy Japanese linkage polymorphism
2010/11/19
Allergy is a common immune disorder characterized by raised IgE levels, which leads to clinical disorders such as asthma, rhinitis and eczema. Our understanding of the pathogenesis of allergic disease...
A Quantitative Immunochromatography Assay of Whole Blood Samples for Antigen-specific IgE -A New Method for Point of Care Testing for Allergens-
Cryptomeria japonica pollen enzyme immunochromatography quantification specific IgE whole blood
2010/11/22
Background: The development of an inexpensive point-of-care testing system for antigen-specific IgE is greatly needed. We, therefore, tried to develop a quantitative enzyme immunochromatography assay ...
Cross-reactive Carbohydrate Determinant Contributes to the False Positive IgE Antibody to Peanut
anaphylaxis cross-reactive carbohydrate determinant food hypersensitivity immunoglobulin E peanut hypersensitivity
2010/11/22
Social education about the features of peanut allergy is needed in Japan. Anti-CCD IgE antibody was suggested to be one of the mechanisms contributing to the false positive detection of peanut IgE. De...
IgE Cross-reactivity between Fish Roe(Salmon, Herring and Pollock) and Chicken Egg in Patients Anaphylactic to Salmon Roe
anaphylaxis chicken egg cross-reactivity food allergy salmon roe
2010/11/19
There were positive correlations between SR and HR or PR, but none between SR and salmon or CE. In the ELISA study using sera from two patients with SR anaphylaxis, IgE-binding to SR was inhibited mor...