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搜索结果: 1-15 共查到国际动态 内科学相关记录72条 . 查询时间(1.731 秒)
造血干细胞(HSCs)在人类整个生命周期中再生血细胞,为了维持其健康状态,HSCs特别依赖于蛋白质稳态。然而,HSCs如何清除错误折叠的蛋白质尚不清楚。近期,加州大学圣地亚哥分校与拉霍亚免疫学研究所的一项联合研究发现,HSCs优先将错误折叠的蛋白质运输到聚集体中,并依赖聚集体自噬在体内维持蛋白质稳态。研究成果发表在《Cell Stem Cell》期刊,标题为“Hematopoietic stem ...
血脑屏障(BBB)破坏与多种中枢神经系统疾病有关,体外BBB模型有利于研究BBB转运机制及其对外部应激事件的响应。但到目前为止,使用模型来研究BBB的能力仍然有限。近期,苏黎世联邦理工学院的研究人员开发了一种基于人体细胞且高度集成的开放式微流体3D BBB模型,该模型带有透明的跨内皮电阻(TEER)传感器,可以实时、高分辨率地监测BBB的结构变化。研究成果发表在《Advanced Science》...
Every day, billions of red blood cells pass through the spleen, an organ that is responsible for filtering out old or damaged blood cells. This task is made more difficult when the blood cells are mis...
急性髓性细胞白血病(AML)是一种侵袭性血癌,预后较差。Fms样酪氨酸激酶受体3(FLT3)是AML中异常激活的主要致癌受体酪氨酸激酶之一。尽管目前针对FLT3相关抑制剂的研究日趋深入,越来越多的新型抑制剂进入了临床试验,但是仍然有特异性不高、药物相关不良反应以及药物耐药等局限性。
全球范围内高血压患者约有13亿,其中10%的患者在接受了3种以上不同种类降血压药治疗后病情仍得不到有效控制。瑞士和比利时的科研人员联合研制了一款新型降血压药,相关成果在《Lancet》发表,论文的标题为:Dual endothelin antagonist aprocitentan for resistant hypertension: a multicentre, blinded, random...
In the summer of 2010, Bill Ludwig and Doug Olson were battling an insidious blood cancer called chronic lymphocytic leukemia (CLL). They’d both received numerous treatments, and as remaining options ...
Researchers have discovered how to “turn off” a key driver of aortic stenosis – the narrowing of the heart’s aortic valve – identifying for the first time the biological process behind certain instanc...
A Cornell-led research team’s improved cell therapy device effectively secreted insulin and controlled blood sugar in diabetic mice for up to six months – showing promise for the possibility of an eff...
2007年7月5日至6日,“中法心血管分子医学论坛(China-France Forum on Cardiovascular Research)”在北京大学召开。本次论坛共设8个专题,22个报告,内容涵盖心血管疾病的分子遗传机制、microRNA与心血管疾病、离子通道与心血管疾病、受体信号转导与心血管疾病、细胞第二信使与心血管疾病、线粒体与心血管疾病、血管生物学及心脏保护机制等热点课题。
根据发表在2007年5月28日的刊物《内科学文献》(Archives of Internal Medicine)上的文章,用大豆蛋白替代食物中的其它蛋白能降低更年期后妇女血压,并且还能减少妇女血液中的胆固醇含量。
May 8, 2007,A one-time chiropractic adjustment of a misaligned neck vertebra has been shown to significantly reduce blood pressure in people with hypertension, according to a pilot study by University...
May 21, 2007,A new study has found that if the decrease is outside that range -- either less than 10 percent or more than 20 percent -- the patient faces a higher risk of heart attacks, strokes and ki...
May 23, 2007,The U.S. Food and Drug Administration (FDA) has asked manufacturers to include a new boxed warning on the product labeling of all gadolinium-based contrast agents which are used to enhanc...
May 21, 2007,During the first 24 hours of invasion by the malaria-inducing parasite Plasmodium falciparum, red blood cells start to lose their ability to deform and squeeze through tiny blood vessels-...
7 May 2007,In the largest study of its kind, research led by the University analysed hospital treatment and outcomes for 44,372 patients admitted to 113 hospitals in 14 countries with heart attacks or...

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