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Immunoexpression of Cathepsin D and S100A4 Protein and Their Molecular Subtyptes in Canine Mammary Carcinomas
Cathepsin Mammary Tumors Metastasis-Associated Proteins Molecular Subtypes S100 Protein
2013/2/19
Cathepsin D (CD), a lysosomal protease, and S100A4 protein, a calcium binding motif, are considered to be involved in metastasis in various human cancers. No data regarding such proteins are available...
Molecular Genetic Perspectives on the Origin of the Lyngngam Tribe of Meghalaya, India
Austro-Asiatics Admixture Autosomal STRs Y-Chromosome Markers MtDNA HVS-I and II Sequences
2013/1/28
Meghalaya, one of the Northeast Indian states, is inhabited by two major tribal clusters, Khasi and Garo. The disputed origin of the Lyngngam tribe of Meghalaya is a result of their geographic distrib...
HIV-complicated meningovascular syphilis: Atypical symptoms with promising result using low molecular weight heparin
Meningovascular Syphilis HIV
2013/2/20
Both WHO and the CDC of Taiwan have reports indicating a dramatic increase in incidence of both syphilis and HIV. With their co-infection, neurosyphilis will become a major issue, and meningovascular ...
Nature Structural & Molecular Biology发表中国科学院生物物理研究所肉碱膜转运蛋白CaiT三维结构研究成果（图）
Nature Structural & Molecular Biology 膜转运蛋白CaiT
2010/4/1
2010年3月28日，生物物理研究所江涛研究员课题组在 Nature Structural & Molecular Biology杂志在线发表了题为“Crystal Structure of the Carnitine Transporter and Insights into the Antiport Mechanism ”的文章。该研究解析了肉碱膜转运蛋白CaiT的三维结构，并对其分子机制进行...
Nanoparticle’s Size Effect on Its Translocation Across a Lipid Bilayer: A Molecular Dynamics Simulation
Size Nanoparticle Molecular Dynamics Lipid Bilayer
2010/7/16
Understanding the interaction between nanoparticles (NPs) and cell membranes (dipalmitoylphosphatidylcholine or DPPC bilayers) is important for the design of drug delivery systems and provides insight...
Molecular Mechanisms Regulating mRNA Stability: Physiological and Pathological Significance
mRNA stability AU-rich elements AU-binding proteins RNA interference microRNA computational biology
2009/12/24
The cytoplasmic level of a messenger RNA, and hence protein, depends not only upon its rates of synthesis,processing, and transport, but its decay rate as well. mRNA decay rates are frequently not sta...
A Distributed Database for Bio-Molecular Images
Distributed Database Bio-Molecular Images
2009/12/23
Information technology research has played a significant
role in the genomics revolution over the past decade,
from aiding with large-scale sequence assembly to automating
gene identification to ef...
Advances in Molecular Labeling, High Throughput Imaging and Machine Intelligence Portend Powerful Functional Cellular Biochemistry Tools
microscopy protein activity pattern analysis cellular diagnostics
2009/12/23
Cellular behavior is complex. Successfully understanding systems at ever-increasing complexity isfundamental to advances in modern science and unraveling the functional details of cellular behavior ...
Modeling and Reconstruction of Mixed Functional and Molecular Patterns
Modeling Mixed Functional Molecular Patterns
2009/9/8
Functional medical imaging promises powerful tools for the visualization and elucidation of important disease-causing biological processes in living tissue. Recent research aims to dissect the distrib...
Synthesis and Bioconjugation of Gold Nanoparticles as Potential Molecular Probes for Light-Based Imaging Techniques
Synthesis Bioconjugation Potential Molecular Probes
2009/9/7
We have synthesized and characterized gold nanoparticles (spheres and rods) with optical extinction bands within the “optical imaging window.” The intense plasmon resonant driven absorption and scatte...
A Penalized Linear and Nonlinear Combined Conjugate Gradient Method for the Reconstruction of Fluorescence Molecular Tomography
Fluorescence Molecular Tomography A Penalized Linear
2009/9/7
Conjugate gradient method is verified to be efficient for nonlinear optimization problems of large-dimension data. In this paper, a penalized linear and nonlinear combined conjugate gradient method fo...
Development of a Confocal Optical System Design for Molecular Imaging Applications of Biochip
Molecular Imaging Biochip
2009/9/7
A novel confocal optical system design and a dual laser confocal scanner have been developed to meet the requirements of highly sensitive detection of biomolecules on microarray chips, which is charac...
Molecular Image Segmentation Based on Improved Fuzzy Clustering
Molecular Image Segmentation Improved Fuzzy Clustering
2009/9/7
Segmentation of molecular images is a difficult task due to the low signal-to-noise ratio of images. A novel two-dimensional fuzzy C-means (2DFCM) algorithm is proposed for the molecular image segment...
Recent Advances in Molecular Imaging.
A Wavelet-Based Multiresolution Reconstruction Method for Fluorescent Molecular Tomography
Fluorescent Molecular Tomography Multiresolution
2009/9/4
Image reconstruction of fluorescent molecular tomography (FMT) often involves repeatedly solving large-dimensional matrix equations, which are computationally expensive, especially for the case where ...