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Factored expectation propagation for input-output FHMM models in systems biology
input output factored hidden Markov models approximate inference variational inference expectation propagation systems biology microarray data
2013/6/14
We consider the problem of joint modelling of metabolic signals and gene expression in systems biology applications. We propose an approach based on input-output factorial hidden Markov models and pro...
Deriving chemosensitivity from cell lines: Forensic bioinformatics and reproducible research in high-throughput biology
Microarrays, reproducibility forensic bioinformatics
2010/10/19
High-throughput biological assays such as microarrays let us ask very detailed questions about how diseases operate, and promise to let us personalize therapy. Data processing, however, is often not d...