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Usefulness of Wheat and Soybean Specific IgE Antibody Titers for the Diagnosis of Food Allergy
food hypersensitivity IgE probability curve soybean wheat
2010/11/16
Background: Since the first suggestion of threshold values for food specific IgE antibody levels in relation to clinical reactivity, several authors have proposed different threshold values for differ...
Polyclonal IgE Induces Mast Cell Survival and Cytokine Production
allergy antibodies cell activation human mast cells/basophils
2010/11/16
Background: Ag-dependent activation of IgE-bearing mast cells is a critical first step in immediate hypersensitivity and other allergic responses. Recent studies have revealed Ag-independent effects o...
Enhanced Production of IgE Anti-Japanese Cedar Pollen Specific Antibodies by Peripheral Blood B Cells from Patients with Japanese Cedar Pollinosis
B cells class switching ELISA immobilized anti-CD3 Japanese cedar pollen
2010/11/17
Background: IgE antibodies against Japanese cedar pollen (JCP) play an important role for the pathogenesis of the cedar pollinosis, but the mechanism of their production has been unclear. We explored ...
Correlations between Alder Specific IgE and Alder-related Tree Pollen Specific IgE by RAST Method
alder allergenicity beech birch oak RAST
2010/11/17
Background: Wild birch trees grow in limited areas in Japan and are not a common aero-allergen. However, many patients who do not live in the area show positive birch pollen Radioallergosorbent Test (...
Regulatory mechanisms of human IgE synthesis
activation-induced cytidine deaminase adaptor molecule germline Cε transcription IgE isotype switching switch recombination machinery
2010/11/24
The induction of allergen-specific IgE synthesis requires the cognate interactions between B and T helper (Th) 2 cells. The B cell-activating signal for IgE synthesis is delivered through interleukin ...
Non-IgE,-IgG4 Antibody to Japanese Cedar Pollen Allergens: Comparison of Its Prevalence and Titers between Pollinosis Patients and Non-Patients
IgG4 antibody in non-patients Japanese cedar pollinosis non-IgE reverse-sandwich ELISA
2010/11/19
We detected specific non-IgE,-IgG4 in both the patients and non-patients. In comparison to the IgE antibody, which was detected in a small proportion of the non-patients with low titers, the non-IgE,-...