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siRNA Targeted to p53 Attenuates Ischemic and Cisplatin-Induced Acute Kidney Injury
acute kidney injury siRNA
2014/12/11
Proximal tubule cells (PTCs), which are the primary site of kidney injury associated with ischemia or nephrotoxicity, are the site of oligonucleotide reabsorption within the kidney. We exploited this ...
Coronary Artery Bypass Surgery and Acute Kidney Injury: Impact of the Off-Pump Technique
Acute kidney injury Coronary artery bypass grafting Off-pump
2015/9/25
Background: Acute kidney injury (AKI) is a common major complication after coronary artery bypass grafting (CABG) especially when the cardiopulmonary bypass is performed. This study was conducted to e...
The effect of Nitroprusside on the renal ischaemia-reperfusion injury
Nitroprusside Ischaemia-reperfusion
2009/12/24
Nitric oxide (NO) is implicated as an important mediator of, or intermediary in, inflammation, immunity and neurotransmission. In the kidney, No is involved in haemodynamic regulation, control of vasc...