搜索结果: 1-15 共查到“pathway”相关记录33条 . 查询时间(0.041 秒)
Faulty genomic pathway is linked to schizophrenia developing in utero,study finds
Faulty genomic pathway schizophrenia
2017/3/14
The skin cells of four adults with schizophrenia have provided an unprecedented “window” into how the disease began while they were still in the womb, according to a recent paper in Schizophrenia Rese...
Transcription factor-pathway co-expression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma
coexpression cell cycle arrest multiple myeloma hyperdiploid
2016/1/25
Multiple myeloma is a hematological cancer of plasma B cells and remains incurable. Two major subtypes of myeloma, hyperdiploid MM (HMM) and non-hyperdiploid MM (NHMM), have distinct chromosomal alter...
Transcription factor-pathway co-expression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma
coexpression cell cycle arrest multiple myeloma hyperdiploid
2016/1/20
Multiple myeloma is a hematological cancer of plasma B cells and remains incurable. Two major subtypes of myeloma, hyperdiploid MM (HMM) and non-hyperdiploid MM (NHMM), have distinct chromosomal alter...
Effect of Patient-Focused Clinical Pathway on Anxiety, Depression and Satisfaction of Patients With Coronary Artery Disease: A Quasi-Experimental Study
Coronary Artery Disease Patient Satisfaction Anxiety Depression Clinical Pathways
2015/11/9
Background: Coronary artery diseases (CAD) are associated with psychological problems such as anxiety and depression in patients. Thus, management of these problems can consider as an important interv...
Prospective association of fatty acids in the de novo lipogenesis pathway with risk of type 2 diabetes: the Cardiovascular Health Study
diabetes mellitus fatty acids metabolism biomarker diet
2018/12/20
Background: Experimental evidence suggests that hepatic de novo lipogenesis (DNL) affects insulin homeostasis via synthesis of saturated fatty acids (SFAs) and monounsaturated fatty acids (MUFAs). Few...
Regenerative Architecture: A Pathway Beyond Sustainability
Architecture Sustainability Green-Building Permaculture
2014/10/29
The current paradigm in the field of architecture today is one of degeneration and obsolete building technologies. Regenerative architecture is the practice of engaging the natural world as the medium...
The PI3K/AKT Pathway and FOXO3a Transcription Factor Mediate High Glucose-Induced Apoptosis in Neonatal Rat Ventricular Myocytes
Myocytes Cardiac Apoptosis gleditsioside B
2015/10/12
Background:: PI3K/AKT pathway plays major roles in regulating cardiomyocyte metabolism. The roles of PI3K/AKT pathway and FOXO3a in mediating high glucose-induced apoptosis in cardiomyocytes remain un...
Identifying Work Setting Profile Factors From the Career Pathway Evaluation Program
pharmacist career work setting profile pharmacist survey
2018/6/28
Objectives. To describe the work factors associated with 28 different career areas as reported by pharmacists who responded to the American Pharmacists Association (APhA) Career Pathway Evaluation Pro...
Aged Garlic Extract Reduces ROS Production and Cell Death Induced by 6-Hydroxydopamine through Activation of the Nrf2-ARE Pathway in SH-SY5Y Cells
Aged Garlic Extract (AGE) 6-OHDA ROS Nrf2-ARE Pathway SH-SY5Y Cells
2013/2/19
Many degenerative or pathological processes, such as aging, cancer and coronary heart disease, are related to reactive oxygen species (ROS) and radical-mediated reactions. We examined the effectivenes...
Effect of Iron-Mediated Oxidative Stress on Insulin Resistance Through the Forkhead Box-Containing Protein O Subfamily-1 (FOXO-1) Pathway in Chronic Hepatitis C
Chronic Hepatitis C Gluconeogenesis Insulin Resistance Iron Metabolism Oxidative Stress
2013/1/29
Aims: Chronic hepatitis C virus (HCV) infection is often associated with glucose metabolic disorders and iron overload. It has recently been shown that reactive oxygen species (ROS) increase gluconeog...
基于pathway谱对药物重定位的探讨
药物重定位 pathway谱 药理功能 药物-疾病关系
2013/8/15
新药开发一直面临着高投入低产出的困境. 药物重定位(drug repositioning)是解决这一问题的有效方法, 因而成为现今药物研究的热点之一. 目前流行的方法主要是基于药物小分子的相似性或关联性(化学结构、副作用、表达谱和小分子-蛋白作用关系等), 预测药物的新功能. 由于仅仅依赖药物-药物之间的关系, 这些新功能限制在现有药物的功能空间之内. 本研究中提出一种以疾病为导向, 基于path...
Rescuing a broken heart: A tale of two Models of Neural Crest deficiency and its impact on In Utero Heart function and Embryonic Survival via the Beta-Adrenergic pathway
pax3 beta-adrenergic embryonic cardiac function
2015/5/21
Congenital heart defects occur in approximately one percent of births every year, which makes it the most frequently occurring congenital defect in patients. The aim of this project was to use two mut...
Distal common pathway in atrioventricular node reentrant tachycardia
AVNRT Distal common pathway Paroxysmal supraventricular tachycardia (PSVT) EPS
2009/12/25
Anotomical boundary of atrioventricular node reentrant tachycardia (AVNRT) is composed of fast and slow pathways right atrium in upper turnaround and common distal pathway in lower turnaround. We perf...
Central America Field Epidemiology Training Program (CA FETP): a pathway to sustainable public health capacity development
Central America Field Epidemiology Training Program pathway public health capacity development
2009/9/27
The Central America Field Epidemiology Training Program (CA FETP) is a public health capacity-building training programme aimed at developing high-caliber field epidemiologists at various levels of th...