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单一延长应激对Wistar大鼠海马Calcineurin表达的影响
创伤后应激障碍 单一延长应激 海马 Calcineurin
2020/11/12
探讨创伤后应激障碍模型-单一延长应激对Wistar大鼠海马钙调神经磷酸酶（Calcineurin,CaN）表达的影响。方法 将Wistar大鼠（n=30）随机分为单一延长应激组（n=15）和对照组（Control,n=15）。前者对大鼠实施国际公认的创伤后应激障碍（posttraumatic stress disorder，PTSD）动物模型方法-单一延长应激（Single-Prolonged S...
Decreased Activity in Neuropathic Pain Form and Gene Expression of Cyclin-Dependent Kinase5 and Glycogen Synthase Kinase-3 Beta in Soleus Muscle of Wistar Male Rats
Neuropathic Pain Soleus Muscle CDK5 Protein Kinase
2015/11/6
Background: The relationship between decreased activity/neuropathic pain and gene expression alterations in soleus muscle has remained elusive.
探讨海分枝杆菌菌壁蛋白组特性及对Wistar大鼠致病免疫学特征，提高对海分枝杆菌致病机制的认识。方法 (1)将临床分离的海分枝杆菌经过培养7～10 d后，挑取培养的菌落，加入到0.9%氯化钠液体中，离心、PBS冲洗、超声破碎制备菌壁蛋白。将制备好的样品蛋白进行双向电泳，凝胶图像分析。(2)应用McFarland比浊法，制备菌液，估计所配制的细菌剂量浓度。选取雄性Wistar大鼠45只，数字随机法分...
不同浓度谷氨酸钠摄入对Wistar大鼠代谢及胰岛细胞凋亡的影响
谷氨酸钠 血糖 胰岛素 糖尿病
2013/11/12
探索不同浓度谷氨酸钠(MSG)摄入对大鼠代谢及胰岛细胞凋亡的影响。方法 将40只Wistar 大鼠随机分为对照组、MSG标准剂量组、MSG 4倍标准剂量组、MSG 8倍标准剂量组，每组10只。对照组给予生理盐水灌胃，MSG组给予自配的MSG溶液灌胃，每周空腹取尾静脉血1次，测血糖、甘油三酯、总胆固醇水平，于33周取颈动脉血测其血糖、胰岛素、甘油三酯、总胆固醇水平。结果 不同组间血糖水平差异...
Evaluation of Biochemical, Hematological and Histological Parameters in Non Diabetic and Diabetic Wistar Rats Fed with Monosodium Glutamate
MSG Glutamate Wistar Rat Diabetes
2013/1/29
The parenteral or oral administration of monosodium glutamate (MSG) has been reported to have a deleterious effect on the hypothalamic arcuate nucleus, which changes appetite control. This alteration ...
Pinealectomy and Exogenous Melatonin Regulate Anxiety-Like and Depressive-Like Behaviors in Male and Female Wistar Rats
Pinealectomy Melatonin Sex Dependent Anxiety Depression Behavioral Tests
2013/1/30
The main objective of this work was to 1) study the influence of endogenous melatonin (Mel) abolishment via pinealectomy and 2) explore exogenous Mel effect on anxiety-like and depressive-like behavio...
Synthesis and Influence of Two Quinoxalinone Derivatives on Anxiety- and Depressive-Like Responses in Wistar Rat
Depression Anxiety Quinoxalinone Derivatives Locomotor Activity Wistar Rats
2013/1/30
Two new quinoxalinone derivatives have been synthesized adopting the HONG method, and investigated for some neuropharmacological effects (anxiety- and depressive-like responses) in rats. The present e...
Is a Divergent Central Serotonergic Activity Responsible for Either Despair or Learning Behavior in Intact Wistar or Sprague-Dawley CD Rats, Respectively? A Concomitant Behavioral and Electrochemical Analysis
Rat Strains Behavior Electrochemistry Fluoxetine Serotonin Platelets
2013/2/23
Behavioral observations combined with electrochemical analysis have been performed in Wistar or Sprague-Dawley CD rats in the attempt to clarify earlier controversial behavioral reports. In particular...
Application of Pulsed Magnetic Stimulation for Recovery from Muscle Fatigue in Hypokalemic and Normal Wistar Rats
muscle fatigue pulsed magnetic stimulation hypokalemia rehabilitation
2009/8/24
In order to study the availability of pulsed magnetic stimulation (pMS) for recovery of acute muscle fatigue, evoked potential were recorded from soleus (slow-twitch fiber type, fatigue-resistant) and...
Suramin Increased Telomerase Activity in the C6 Glioma/ Wistar Experimental Brain Tumor Model
chemosensitivity C6 glioma hormesis suramin telomerase
2009/4/20
Glioblastoma multiforme (GBM) is the most treatment-resistant glioma variant. Significant roles for telomerase in etiology, recurrence and drug resistance of GBM have been highlighted. Suramin (Bayer...
Anti-hyperglycemic effects of plum in a rat model of obesity and type 2 diabetes, Wistar fatty rat
Anti-hyperglycemic effects obesity type 2 diabetes Wistar fatty rat
2009/3/3
Dried plums, considered a healthy food in the West and used as medicine in India, contain phenolic compounds with protective actions against age-related diseases. Effects of oral plum ekisu (concent...
ENHANCEMENT OF CUTANEOUS WOUND HEALING BY METHANOLIC EXTRACTS OF AGERATUM CONYZOIDES IN THE WISTAR RAT.
Wound healing Ageratum conyzoides Effect of
2008/4/28
In a bid to test the wound healing effect of a crude methanolic extract
of Ageratum conyzoides (Linn.), 20 animals were divided into two groups of
ten animals each representing control and e...