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Microcurrent Electrical Neuromuscular Stimulation Facilitates Regeneration of Injured Skeletal Muscle in Mice
Muscle injury regenerative potential
2015/8/28
Conservative therapies, mainly resting care for the damaged
muscle, are generally used as a treatment for skeletal muscle
injuries (such as muscle fragmentation). Several past studies
reported t...
Efflux of Creatine Kinase from Isolated Soleus Muscle Depends on Age, Sex and Type of Exercise in Mice
Skeletal muscle eccentric contractions muscle damage CK activity
2015/8/28
Elevated plasma creatine kinase (CK) activity is often used as an
indicator of exercise-induced muscle damage. Our aim was to
study effects of contraction type, sex and age on CK efflux from
iso...
Proteomic analysis of plasma after branched chain enriched mixture supplementation in mice
Amino acids Proteome Dietary supplements
2015/7/27
Branched chain amino acid (BCAA) supplementation is a recently identified strategy to promote longevity in mice. A proteomic approach was used to identify proteins which are differentially expressed i...
THE EFFECT OF ETHANOL ON IMPULSIVITY IN HIGH ALCOHOL PREFERRING MICE
ETHANOL HIGH ALCOHOL PREFERRING MICE
2015/5/21
Impulsivity is associated with addiction in many human studies. Delay discounting (DD) is often used to measure impulsive choice in humans and animals. In DD testing, a small immediate reward is pitte...
Loss of Adipocyte VEGF Impairs Endurance Exercise Capacity in Mice
INSULIN FREE FATTY ACIDS GLYCEROL SKELETAL MUSCLE WHITE ADIPOSE TISSUE
2017/4/20
Purpose: Reducing vascular endothelial growth factor (VEGF) in adipose tissue alters adipose vascularity and metabolic homeostasis. We hypothesized that this would also affect metabolic responses duri...
Adipose Tissue Insulin Action and IL-6 Signaling after Exercise in Obese Mice
INFLAMMATION MACROPHAGE ACUTE EXERCISE ADIPOSE TISSUE
2017/4/20
Introduction: Adipose tissue insulin action is impaired in obesity and is associated with inflammation, macrophage infiltration, and polarization toward a proinflammatory phenotype. Acute exercise can...
Investigating the role of extrasynaptic GABAA receptors located in the infralimbic cortex in the binge-like alcohol intake of male C57BL/6J mice
Mouse Alcohol GABA Binge Drinking Infralimbic Cortex
2015/1/9
Extrasynaptic GABAA receptors, often identified as those containing both α4 and δ subunits, appear to be a target for the actions of alcohol (ethanol) at relatively low concentrations, perhaps suppres...
Exercise-Induced Changes in the Cortical Bone of Growing Mice Are Bone and Gender Specific
mechanical properties pQCT matrix changes
2014/11/6
Fracture risk and mechanical competence of bone are functions of bone mass and tissue quality, which in turn are dependent on the bone's mechanical environment. Male mice have a greater response to no...
Short-Term Exercise In Mice Increases Tibial Post-Yield Mechanical Properties While Two Weeks of Latency Following Exercise Increases Tissue-Level Strength
running mechanical properties histomorphometry extracellular matrix
2014/11/6
We have previously shown that exercise during growth increases post-yield deformation in C57BL6/129 (B6;129) male tibiae at the expense of reduced pre-yield deformation and structural and tissue stren...
Inbred Strain-Specific Effects of Exercise in Wild Type and Biglycan Deficient Mice
Transgenic Mechanical properties Exercise Micro CT Raman
2014/11/6
Biglycan (bgn)-deficient mice (KO) have defective osteoblasts which lead to changes in the amount and quality of bone. Altered tissue strength in C57BL6/129 (B6;129) KO mice, a property which is indep...
Inbred Strain-Specific Response to Biglycan Deficiency in the Cortical Bone of C57BL6/129 and C3H/He Mice
inbred mice mech anical properties mCT PCR Raman histomorphometry
2014/11/6
Inbred strain-specific differences in mice exist in bone cross-sectional geometry, mechanical properties, and indices of bone formation. Inbred strain-specific responses to external stimuli also exist...
Deletion of the Bax Gene Severley Impairs Sexual Behavior and Modestly Impairs Motor Function In Mice
Behavior Bax Sexual Motor
2014/10/31
During neural development, nearly 50% of all newly generated neurons undergo cell death after making provisional contact with their target cells. The functional consequences of eliminating this neuron...
Metabolic Adaptations in the Liver of Born Long-Distance Running Mice
PPAR DELTA SIRTUIN 1 LIVER METABOLISM GLUCONEOGENESIS, LIPOGENESIS
2017/7/17
Purpose: Long-distance runners have increased needs of energy supply. To unravel genetically based mechanisms required for efficient energy supply, we have analyzed hepatic metabolism of mice characte...
Synergistic effects of Isatis tinctoria L. and tacrolimus in the prevention of acute heart rejection in mice
satis tinctoria L mice
2013/6/26
Although immunosuppressive treatments are available for acute cardiac rejection no viable treatment exists for long-term cardiac graft failure. Moreover, the extended use of calcineurin inhibitor immu...
Oral Quercetin Supplementation Lowers Plasma sICAM-1 Concentrations in Female db/db Mice
Quercetin Inflammation Insulin Resistance Obesity Adiponectin
2013/2/19
Background: Flavonoids are documented for their potential anti-adipogenic, anti-inflammatory and anti-diabetic effects. Quercetin, one of the most abundant flavonoids in edible plants, was investigate...