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汕头大学医学院药理学精品课程 gene polymorphism and drug and disease[1]
汕头大学 医学院 药理学 精品课程 gene polymorphism and drug and disease 1
2013/11/7
汕头大学医学院药理学精品课程 gene polymorphism and drug and disease[1]。
Association between TNF-Alpha (-857) Gene Polymorphism and Susceptibility to Tuberculosis
Tuberculosis TNF-α Gene Polymorphism
2015/9/23
Background: TNF-α as a pro-inflammatory cytokine play a key role in host defense against tuberculosis (TB). Presence of mutation in TNF-α gene can influence the effectiveness, performance and capabili...
Methylenetetrahydrofolate Reductase Gene Polymorphism and Homocysteine Level in Patients with Pseudoexfoliation and Pseudoexfoliation Glaucoma in Southern Iran
Pseudoexfoliation Pseudoexfoliation glaucoma Gene Polymorphism
2015/9/18
Background: Pseudoexfoliation (PEX) syndrome leads to elevated intraocular pressure and consequent glaucomatous damage of the optic nerve. This study was performed to investigate the frequency of MTHF...
TP53 codon 72 Gene Polymorphism Paradox in Associated with Various Carcinoma Incidences, Invasiveness and Chemotherapy Responses
TP53 codon 72 apoptosis
2009/4/10
TP53 is the most common mutated gene in human cancers. Approximately half of all human malignancies exhibit TP53 mutations. The TP53 codon 72 polymorphism is a single-nucleotide polymorphism (SNP) in ...
磺酰脲类受体基因多态性与2型糖尿病的相关性研究Study on the Relationship between Sulfonylurea Receptor 1 Gene Polymorphism and Type 2 Diabetes Mellitus
2型糖尿病 磺酰脲类受体1 基因多态性
2008/1/10
摘要 研
究磺酰脲类受体1（SUR1）基因外显子16-3c/t多态性在中国某南方汉族人群中是否为2型糖尿病的致病基因座。采用聚合酶链反应-限制酶酶切片段长度多态性（PCR-RFLP）方法对南方汉族46个2型糖尿病高发家系成员的SUR1基因外显子16的多态性进行分析。利用Mantel-Haenszel分层分析研究该基因座多态性与2型糖尿病的关系。在高发家系人群中，SUR1基因外显子16-3c/t多...
载脂蛋白E基因多态性与2型糖尿病脑梗死的关系Association Study of Apolipoprotein E Gene Polymorphism and Cerebral Infarction in Type 2 Diabetic Patients
载脂蛋白E 基因多态性 2型糖尿病 脑梗死
2008/1/6
摘要研究载脂蛋白E (ApoE) 基因多态性与中国东北汉族2型糖尿病合并脑梗死的关系。采用聚合酶链反应－限制性片段长度多态性（PCR-RFLP）技术，检测了208例个体的ApoE基因多态性，其中对照（CON）组69例，2型糖尿病无大血管病变（T2DM）组67例和2型糖尿病合并脑梗死（T2DMCI）组72例；同时测定了其中70例T2DMCI患者的血脂含量。CON组等位基因频率为：ε2 9.6％、ε3...
Association of Angiotensin Converting Enzyme (ACE) Gene Polymorphism and Diabetic Nephropathy
Angiotensin converting enzyme Genetic polymorphism Insertion/deletion Diabetic nephropathy Iran
2010/2/1
Angiotensin I-converting Enzyme (ACE) gene polymorphism; genotype DD or D allele may be involved with an increased susceptibility to type 2 diabetes and diabetic nephropathy (DN). We examined the freq...