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An integrative systems biology approach for analyzing liver hypermetabolism
hypermetabolism gene expression regulation
2009/12/24
Severe injury and other disease conditions (cancer, diabetes) lead to a hypermetabolic
state featuring increased turnover of proteins, fatty acids and carbohydrates. Prolonged
hypermetabolism is a...
Networks, Biology and Systems Engineering: A Case Study in Inflammation
Systems biology transcriptional regulation disease models inflammation
2009/12/24
Biological systems can be modeled as networks of interacting components across multiple scales. A central problem in computational systems biology is to identify those critical components and the rule...