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北京大学工学院生物医学工程系段小洁课题组及合作者在MRI兼容神经电极及DBS-fMRI联用揭示DBS对大脑调制效应方面取得重要进展（图）
北京大学工学院 生物医学工程 段小洁 MRI兼容神经电极 DBS-fMRI DBS 大脑调制效应
2020/4/16
近日，北京大学工学院生物医学工程系段小洁研究员课题组与中国科学院神经科学研究所、脑科学与智能技术卓越创新中心梁智锋课题组合作，研制了一种基于石墨烯纤维的高度兼容MRI的DBS刺激电极，在帕金森症大鼠模型上，实现了DBS下整脑范围内完整fMRI脑激活图谱的扫描，发现了DBS治疗帕金森症效果与不同脑区激活的关联关系。该石墨烯纤维DBS电极具有高于同尺寸铂铱（PtIr，临床DBS所用的材料）电极70倍的...
基于离散小波变换的fMRI数据特征提取
磁共振成像 特征提取 离散小波变换 相关分析
2014/6/5
设计一种灵敏度高且处理速度快的fMRI数据小波分析方法。方法 先用离散小波变换和频谱分析确定有用信号存在的小波分解尺度,也即特征尺度;再对实验数据进行离散小波分解,重构时将非特征尺度里的小波系数设置为0;再以相关分析对小波重构信号进行激活检测。结果 对视觉数据的分析结果显示,新方法的灵敏度与基于平稳小波变换、SPM2方法相当,而优于基于提升小波变换的方法;新方法的处理速度与基于提升小波变换的方法相...
BOLD Noise Assumptions in fMRI
BOLD fMRI
2009/9/8
This paper discusses the assumption of Gaussian noise in the blood-oxygenation-dependent (BOLD) contrast for functional MRI (fMRI). In principle, magnitudes in MRI images follow a Rice distribution. W...
Intervention Models in Functional Connectivity Identification Applied to fMRI
Intervention Models Functional Connectivity Identification fMRI
2009/9/8
Recent advances in neuroimaging techniques have provided precise spatial localization of brain activation applied in several neuroscience subareas. The development of functional magnetic resonance ima...
Cerebral Blood Flow Measurement Using fMRI and PET: A Cross-Validation Study
fMRI PET Cerebral Blood Flow Measurement
2009/9/4
An important aspect of functional magnetic resonance imaging (fMRI) is the study of brain hemodynamics, and MR arterial spin labeling (ASL) perfusion imaging has gained wide acceptance as a robust and...
An fMRI-MEG Integrative Method for Dynamic Imaging of Multiple Cortical Activities
fMRI-MEG integration dynamic imaging visual cortex
2009/6/9
We have developed an fMRI-MEG integrative method that is capable of analyzing spatiotemporal multiple cortical activities. Firstly, activated regions were determined by statistically analyzing fMRI da...
An fMRI-MEG Integrative Neuroimaging Method: Improvements of its Accuracy and Robustness by Suppression of fMRI-invisible Coherent Activities
functional neuroimaging fMRI-MEG integrative analysis spatial filter
2009/6/8
One of possible problems in fMRI-MEG integrative analysis is mismatches between activated regions detected by fMRI and MEG. These mismatches cause serious degradation of estimation accuracy, especiall...