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Expression and Activities of Matrix Metalloproteinases under Oscillatory Shear in IL-1-Stimulated Synovial Cells
Expression Matrix Metalloproteinases
2014/11/13
Matrix metalloproteinases (MMPs) are known to play a critical role in tissue disintegration, and an elevated level of MMPs is observed in synovium and synovial fluid of joints with rheumatoid arthriti...
Exercise Alters Mineral and Matrix Composition in the Absence of Adding New Bone
Mechanical loading Mechanical properties Mineral Collagen Raman spectroscopy
2014/11/6
The mechanical properties of bone are dictated by its amount, distribution and ‘quality’. The composition of the mineral and matrix phases is integral to defining ‘bone quality’. Exercise can potentia...
Stress-Induced Dispersal of Staphylococcus epidermidis Biofilm Is Due to Compositional Changes in Its Biofilm Matrix
Staphylococcus epidermidis Biofilm Composition Detachment Nutrient Limitation
2013/1/29
Biofilm formation is an important virulence factor of Staphylococcus epidermidis. However, little is known about the mechanisms of staphylococcal biofilm dispersal. In the present study, we investigat...
Defining the Role of Matrix Compliance and Proteolysis in Three-Dimensional Cell Spreading and Remodeling
extracellular matrix Proteolysis
2010/1/7
Recent studies have identified extracellular matrix (ECM) compliance as an influential factor in determining the
fate of anchorage-dependent cells. We explore a method of examining the influence of E...
Dispersal of Golgi matrix proteins during mitotic Golgi disassembly
Golgi apparatus Biogenesis Golgin GRASP
2009/12/23
During mitosis, the mammalian Golgi disassembles into
numerous vesicles and larger membrane structures
referred to as clusters or remnants. Following mitosis, the
vesicles and clusters reassemble t...
Total Variation Regularization of Matrix-Valued Images
Total Variation Regularization Matrix-Valued Images
2009/9/7
We generalize the total variation restoration model, introduced by Rudin, Osher, and Fatemi in 1992, to matrix-valued data, in particular, to diffusion tensor images (DTIs). Our model is a natural ext...
Introduction of Sustained Release Opipramol Dihydrochloride Matrix Tablets as a New Approach in the Treatment of Depressive Disorders
compression parameters controlled drug delivery direct compression matrix tablets opipramol 2-HCl
2009/4/20
Opipramol 2-HCl (OP) is used for therapy of general somatoform and anxiety disorders. Conventional tablets in the market contain 50 mg OP to be used once or up to three times a day in effective treat...
Periodontal regeneration in intrabony defects after application of enamel matrix proteins with guided tissue regeneration：An experimental study in dogs
Periodontal regeneration enamel matrix proteins guided tissue regeneration
2009/3/2
The aim of this study was to evaluate the effects of enamel matrix proteins (EMP) at the early stage of wound healing in the periodontal tissues by a combination treatment with guided tissue regener...
The effects of matrix stiffness and RhoA on the phenotypic plasticity of smooth muscle cells in a 3-D biosynthetic hydrogel system
ECM (extracellular matrix) Hydrogel Mechanical properties Polyethylene oxide Smooth muscle cell
2010/1/7
Studies using 2-D cultures have shown that the mechanical properties of the extracellular matrix (ECM) influence cell migration, spreading,
proliferation, and differentiation; however, cellular mecha...
Matrix stiffness affects spontaneous contraction of cardiomyocytes cultured within a PEGylated fibrinogen biomaterial
Cardiac cell therapy Mechanical properties Fibrin Polyethylene glycol Image analysis Hydrogel
2010/1/7
Successful implementation of cardiac cell transplantation for treating damaged myocardium relies on the development of improved
injectable biomaterials. A novel biomaterial technology using PEGylated...
Immobilized Fibrinogen in PEG Hydrogels Does not Improve Chondrocyte-Mediated Matrix Deposition in Response to Mechanical Stimulation
mechanotransduction compressive strain poly(ethylene glycol) bioreactor cartilage
2010/1/7
The present investigation aims to explore the
role of cell-scaffold interactions and whole cell compression
in chondrocyte mechanotransduction using encapsulating
poly(ethylene glycol) (PEG) hydrog...
In Vitro Assessment of Bee Venom Effects on Matrix Metalloproteinase Activity and Interferon Production
Bee Venom Fibrosarcoma Interferon Matrix Metalloproteinase Monocyte
2010/2/3
Controversial immunomodulatory properties of bee venom (BV) have provided an appropriate field for more investigation. The aim of present research was to verify the effects of honeybee venom on matrix...
The Role of Matrix Metalloproteinase-2 in the Remodeling of Cell-Seeded Vascular Constructs Subjected to Cyclic Strain
Tissue engineering Matrix metalloproteinases Mechanical properties Cyclic strain Vascular remodeling
2010/1/7
Tissue engineering offers the opportunity to develop
vascular substitutes that mimic the responsive nature of native
arteries. A good blood vessel substitute should be able to remodel
its matrix in...