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Polyclonal IgE Induces Mast Cell Survival and Cytokine Production
allergy antibodies cell activation human mast cells/basophils
2010/11/16
Background: Ag-dependent activation of IgE-bearing mast cells is a critical first step in immediate hypersensitivity and other allergic responses. Recent studies have revealed Ag-independent effects o...
Allergen-specific T-cell Response in Patients with Phenytoin Hypersensitivity; Simultaneous Analysis of Proliferation and Cytokine Production by Carboxyfluorescein Succinimidyl Ester (CFSE) Dilution Assay
allergen-specific T cell CFSE dilution assay IFN-γ lymphocyte transformation test phenytoin hypersensitivity
2010/11/18
Phenytoin-specific proliferation may be detected with greater sensitivity by the CFSE dilution assay than the conventional LTT. The assay revealed that both CD4+ and CD4- T cells proliferated and prod...
Role of a Th2 cytokine inhibitor in asthma treatment
cough variant asthma eosinophilic airway inflammation interleukin-4 interleukin-5 interleukin-13 steroid-sparing effect
2010/11/22
The airway wall of asthmatic patients is infiltrated with inflammatory cells, consisting chiefly of eosinophils and T lymphocytes. Among these T lymphocytes, Th2 cells are involved in the regulation o...