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Cost-Effectiveness of an Emergency Department Based Early Sepsis Resuscitation Protocol
sepsis emergency medicine
2014/11/28
Background Guidelines recommend that sepsis be treated with an early resuscitation protocol, such as early goal directed therapy (EGDT). Our objective was to assess the cost-effectiveness of implement...
Prognostic Value and Agreement of Achieving Lactate Clearance or Central Venous Oxygen Saturation Goals During Early Sepsis Resuscitation
Fibrin fragment D venous thromboembolism medical decision making tomography spiral computed
2014/11/28
Objectives: Lactate clearance (LC) and central venous oxygen saturation (ScvO2) have been proposed as goals of early sepsis resuscitation. The authors sought to determine the agreement and prog...
Association Between Timing of Antibiotic Administration and Mortality from Septic Shock in Patients Treated with a Quantitative Resuscitation Protocol
sepsis antibiotics septic shock emergency medicine
2014/11/28
Objective We sought to determine the association between time to initial antibiotics and mortality of septic shock patients treated with an emergency department (ED) based early resuscitation protocol...
Outcomes of Patients Undergoing Early Sepsis Resuscitation for Cryptic Shock Compared with Overt Shock
septic shock lactate resuscitation emergency medicine mortality
2014/11/28
Introduction We sought to compare the outcomes of patients with cryptic versus overt shock treated with an emergency department (ED) based early sepsis resuscitation protocol. Methods Pre-planned seco...
Whole blood lactate kinetics in patients undergoing quantitative resuscitation for septic shock
whole blood lactate kinetics septic shock emergency medicine
2014/11/28
Introduction We sought to compare the association of whole blood lactate kinetics with survival in patients with septic shock undergoing early quantitative resuscitation. Methods Preplanned analysis o...
The effect of a quantitative resuscitation strategy on mortality in patients with sepsis: A meta-analysis
sepsis septic shock mortality resuscitation meta-analysis
2014/11/28
Objective Quantitative resuscitation consists of structured cardiovascular intervention targeting predefined hemodynamic end points. We sought to measure the treatment effect of quantitative resuscita...