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中国医学科学院实验血液学国家重点实验室程韩忠朝课题组在Cell Transplant期刊上发表"Human umbilical cord mesenchymal stem cells ameliorate mice trinitrobenzene sulfonic acid (TNBS)-induced colitis"
韩忠朝 课题组 Cell Transplant期刊
2012/2/23
中国医学科学院实验血液学国家重点实验室韩忠朝课题组在Cell Transplant期刊上发表"Human umbilical cord mesenchymal stem cells ameliorate mice trinitrobenzene sulfonic acid (TNBS)-induced colitis."
Histopathological effects of chronic fluorosis on the liver of mice (Swiss albino)
Chronic fluorosis mouse liver histopathology
2010/10/14
Fluoride intake in high doses has toxic effects on various organs. Chronic fluorosis results in tubular degenerations, inflammation, fibrosis, parenchymatous nephritis, cloudy swellings, and dilations...
Amphiregulin Is Not Essential for Ovalbumin-Induced Acute Airway Inflammation in Mice
amphiregulin asthma EGF IgE mast cells
2010/11/12
Background: The number of amphiregulin (AR)-positive mast cells in the bronchial mucosa and the levels of AR in sputum from asthmatic patients have been reported to be increased. In addition, AR can p...
Development and time-course of bleomycin-induced pulmonary fibrosis in NMRI mice
Pulmonary fibrosis NMRI mice
2010/4/7
Bleomycin-induced pulmonary fibrosis is a widely used experimental model for human lung fibrosis. The severity of fibrosis varies among different strains of mice and investigation on different strains...
Effect of Zinc Deficiency on Zinc and Carbohydrate Metabolism in Genetically Diabetic (C57BL/Ksj Db+/Db+) and Non-Diabetic Original Strain (C57BL/Ksj) Mice
Strain zinc depletion diabetic mice (C57BL/KsJdb+/db+) nondiabetic mice (C57BL/KsJ)
2009/6/23
Our aim was to investigate the effect of low dietary zinc intake on zinc and carbohydrate metabolism in type II diabetes. Male, 4–5-week-old, genetically diabetic (C57B/LKsJdb+/db+) and nondiabe...
Enhanced Goblet Cell Hyperplasia in HDC Knockout Mice with Allergic Airway Inflammation
airway remodeling asthma Gob-5 MUC5AC TNF-α
2010/11/16
The number of eosinophils in BALF increased in both the sensitized wild-type mice and Hdc-/- mice with OVA inhalation. In addition, the numbers of alveolar macrophages and lymphocytes in BALF increase...
Effect of Am-80, a novel retinoid derivative, on contact hypersensitivity caused by repeated applications of hapten in mice
2, 4-dinitrofluorobenzene Am-80 contact dermatitis cytokine retinoid
2010/11/25
Some retinoids show an anti-inflammatory action through regulation of transcription of various genes. In the present study, the inhibitory effect of 4-((5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphth...
The effects of genistein, a tyrosine kinase inhibitor on acute and chronic inflammation in diabetic mice
Diabetes Genistein Inflammation Mice Streptozotocin Tyrosine kinase
2010/2/3
The effects of tyrosine kinases on acute and chronic inflammation during diabetes are not fully determined. Therefore, the present study focuses on the effects of genistein, a tyrosine kinase inhibito...
Induction of Experimental Allergic Encephalomyelitis in C57/BL6 Mice:An Animal Model for Multiple Sclerosis
Experimental allergic encephalomyelitis C57/BL6 mice Multiple sclerosis Myelin oligodendrocyte glycoprotein
2010/2/8
Basic research on the autoimmune disease multiple sclerosis has been performed mainly on its animal model namely experimental allergic encephalomyelitis. There are many different approaches establishe...
The Effect of Vitamin E on Splenocytes Apoptosis of Gamma-Irradiated BALB/c Mice
Apoptosis Free Radicals Gamma Radiation Vitamin E
2010/2/8
Apoptosis, a physiologic mechanism to eliminate unwanted cells, is also induced by ionizing irradiation, through production of free radicals. It has been demonstrated that antioxidants such as vitamin...