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Smart Artificial Beta Cells Could Lead to New Diabetes Treatment（图）
Smart Artificial Beta Cells New Diabetes Treatment
2017/11/23
Treating type 1 diabetes and some cases of type 2 diabetes has long required painful and frequent insulin injections or a mechanical insulin pump for insulin infusion. But researchers from the Univers...
Hemoglobin D (Hb D Punjab/ Los Angeles and Hb D Iran) and Co-Inheritance with Alpha- and Beta-Thalassemia in southern Iran
Hemoglobin (Hb) D Punjab Hb D Iran Hb D- beta- thalassemia (thal) Hb D-alpha- thal-1 trait Hb DSickle cell anemia
2015/9/23
Background: Hemoglobin-D (Hb D) is an uncommon structural hemoglobin variant, which is reported to be prevalent in north western India. There are only a few small series, of this entity in the literat...
Serum Folate Level Determination in Major Beta Thalassemia Patients
Beta major thalassemia Folic acid Hemoglobin Folate Trace elements
2009/12/14
Objective: Beta major thalassemia is a variant of beta thalassemia syndrome which could be treated with bone marrow transplantation or if not available, regular blood transfusion. In the later group, ...
目的: 检测幽门螺杆菌( H pylori)阳性消化性溃疡(peptic ulcer, PU)患者胃窦黏膜组织学改变和炎症相关基因核因子kappaB(Nuclear-kappaB, NF-kappaB)、人beta-防御素-2(human beta-denfensin-2, HBD-2)蛋白表达, 探讨胃窦黏膜炎症及NF-kappaB、HBD-2在H pylori相关性PU中的作用及其意义. 方法...
0.05).E-cad在单纯黏液癌和腺管乳头结构黏液癌的表达率为100.0%，而印戒细胞黏液癌和混合细胞黏液癌分别为38.9%和62.5%，显示恶性程度高表达率降低，差异有显著性(P<0.01). beta-cat在胃含黏液癌中显示出恶性程度高其表达强度明显减弱. 结论: hTERT, E-cad和beta-cat阳性表达水平与胃含黏液腺癌组织病理学分型显著相关，对临床判断预后具有重要意义.
目的: 本研究旨在探讨COX-2、beta-cat和MMP-7表达与HNPCC特殊侵袭转移生物学行为间的关系. 方法: 应用免疫组化SP法检测HNPCC(n = 28)、散发性大肠癌(n = 30)和正常大肠黏膜(n = 10)中COX-2, beta-cat和MMP-7的表达情况. 所有标本预先经过hMSH2和hMLH1免疫组化染色筛查, 并结合其临床病理特点进行回顾性分析. 结果: 在HNPC...
Susceptibility of Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Urine Isolates to Fosfomycin, Ciprofloxacin, Amikacin and Trimethoprim-Sulfamethoxazole
Urinary tract infections ESBL Escherichia coli fosfomycin
2009/6/16
Aim: Urinary tract infections (UTIs) caused in particular by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli strains are related with high morbidity and mortality, and treatment is ...
p53、malat1、ki-67和beta-catenin基因mRNA检测在大肠癌分子诊断中的意义
大肠癌 分子诊断 p53 malat1 ki-67 β-catenin 实时荧光定量PCR
2009/2/9
目的: 初步研究多个大肠癌相关基因p53、malat1、ki-67和beta-catenin在大肠癌分子诊断中的意义. 方法: 收集手术切除的新鲜大肠癌组织标本47例、大肠腺瘤组织标本13例, 以及分别和大肠癌、大肠腺瘤对应的正常大肠黏膜组织标本53例, 用实时荧光定量RT-PCR方法检测各基因的Ct值. 结果: p53、malat1在大肠癌组表达量均高于大肠腺瘤组(P = 0.026, P = ...
目的: 探讨食管癌患者E-钙粘蛋白(E-cadherin, E-cad)和beta-连环素(beta-catenint, beta-cat)复合体表达及临床病理特征与食管癌患者术后生存的关系. 方法: 收集1998-2001年本院行食管癌根治术后的标本67例, 应用免疫组织化学S-P法进行E-cad和beta-cat复合体测定, 结合病理学特征与患者生存期进行Kaplan-Meier单因素分析和C...
目的: 探讨分泌型Frizzled相关蛋白2(Secreted Frizzled-related proteins 2, SFRP2)和beta-连接素(beta-catenin)在大肠癌发生、发展中的作用. 方法: 采用免疫组化SP法检测20例正常大肠黏膜、20例非腺瘤性息肉、36例大肠腺瘤和42例大肠癌组织中的SFRP2和beta-catenin蛋白的表达情况, 分析二者表达的差异及其与临床病...
TGF-beta/CTGF在肠纤维化机制中的作用
TGF-beta/CTGF 肠纤维化机制 作用
2009/2/8
肠纤维化是多种炎性肠病比较棘手的并发症, 主要因肠间质细胞的过度增殖及细胞外基质(extracellular matrix, ECM)的异常沉积所致, 转化生长因子(transforming growth factor-beta, TGF-beta)在此过程中起了关键作用. 结缔组织生长因子(connective tissue growth factor, CTGF)作为TGF-beta致纤维化作...