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Evaluation of the Protective Effect of Silibinin Against Diazinon Induced Hepatotoxicity and Free-Radical Damage in Rat Liver
Diazinon Oxidative Stress Antioxidants Histopathology Liver
2015/10/22
Background: Diazinon (0,0-Diethyl 0-(1-6-methyl-2-isoprophyl 4 pyrimidinyl) phosphorothioate) (DI) is a very effective organophosphate pesticide, used widely in agriculture. Consequently, data on pois...
Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat
cyclooxygenase-2 COX-2 COX-1 prostaglandin E2 neuroinflammation blood-brain barrier ischemia stroke matrix metalloproteinase MMP-3 MMP-9 gelatinase B stromelysin-1 oxidative stress indomethacin cyclooxygenase-1 glutathione free radicals MRI
2015/7/29
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-alp...
Creatine supplementation and oxidative stress in rat liver
Creatine supplementation Oxidative stress Enzymes Treadmill exercise
2015/7/28
The objective of this study was to determine the effects of creatine supplementation on liver biomarkers of oxidative stress in exercise-trained rats.Forty 90-day-old adult male Wistar rats were assig...
Effects of a probiotic soy product and physical exercise on formation of pre-neoplastic lesions in rat colons in a short-term model of carcinogenic
probiotic soy product physical exercise pre-neoplastic lesions in rat colons short-term model of carcinogenic
2015/7/16
In this study the influence of moderate or intense physical exercise, alone or in combination with the consumption of a soya product fermented with Enterococcus faecium, on the development of colon ca...
Effect of Taurine Supplementation on the Alterations in Amino Acid Content in Skeletal Muscle with Exercise in Rat
Serine glycine threonine gluconeogenic precursor treadmill
2015/5/7
Taurine included abundantly in skeletal muscle, particularly in the slow-twitch fibers, enhances exercise performance. However, the exact mechanisms for this effect have been unclear. The present stud...
Maternal Exercise Does Not Significantly Alter Adult Rat Offspring Vascular Function
PREGNANCY RUNNING PROGRAMMING CARDIOVASCULAR DISEASE
2017/4/20
Purpose: Research has revealed the role of adverse behaviors during pregnancy on metabolic and cardiovascular health outcomes in offspring. However, minimal attention has been focused on positive pren...
Sprint-Interval Training Induces Heat Shock Protein 72 in Rat Skeletal Muscles
Hindlimb treadmill running enzyme activity fiber type shift hypertrophy
2015/3/18
Previous studies have demonstrated that endurance exercise training increases the level of heat shock proteins (HSPs) in skeletal muscles. However, little attention has been drawn to the effects of hi...
Three Intermittent Sessions of Cryotherapy Reduce the Secondary Muscle Injury in Skeletal Muscle of Rat
Tibialis anterior hypothermia damage
2015/3/18
Although cryotherapy associated to compression is recommended as immediate treatment after muscle injury, the effect of intermittent sessions of these procedures in the area of secondary muscle injury...
Effects of angiotensin (1-7) upon right ventricular function in experimental rat pulmonary embolism
Renin-angiotensin system Angiotensin converting enzyme 2 Angiotensin (1-7) Pulmonary embolism Right ventricle
2014/11/28
Right ventricular (RV) dysfunction contributes to poor clinical prognosis after pulmonary embolism (PE). The present studies evaluate the effects of angiotensin (1-7) (ANG (1-7)) upon RV function duri...
Investigating Antithyroid Effects of Propylthiouracil on the Ischemia and Reperfusion Injury in Rat’ Kidney and Determining the Role of Nitric Oxide in Mediating this Effect
Ischemia Reperfusion Rat,Renal Transplantation
2015/10/15
Background: Renal ischemia/reperfusion injury (IRI) is a major problem in renal transplantation, which occurs during the process of organ retrieval and storage, and is closely associated with acute re...
Effects of Vitamin D and Calcium Supplementation on Micro-architectural and Densitometric Changes of Rat Femur in a Microgravity Simulator Model
Weightlessness Bone Density Osteoporosis Dietary Supplements Calcium Vitamin D
2015/10/13
Background:: Revealing data on the role of vitamin D and calcium supplementation in bone health has led some to suggest that vitamin D and calcium treatment could also play a role in protecting bone a...
The PI3K/AKT Pathway and FOXO3a Transcription Factor Mediate High Glucose-Induced Apoptosis in Neonatal Rat Ventricular Myocytes
Myocytes Cardiac Apoptosis gleditsioside B
2015/10/12
Background:: PI3K/AKT pathway plays major roles in regulating cardiomyocyte metabolism. The roles of PI3K/AKT pathway and FOXO3a in mediating high glucose-induced apoptosis in cardiomyocytes remain un...
The Healing Effect of Arnebia Euchroma in Second Degree Burn Wounds in Rat as an Animal Model
Healing Arnebia euchroma Burn Wound Rat
2015/9/25
Background: Finding more efficient agents with fewer side effects for treatment of burns has always been a concern for researchers. Silver sulfadiazine (SSD), apparently due to its antimicrobial effec...
The Effect of Intra-CA1 Agmatine Microinjection on Water Maze Learning and Memory in Rat
Agmatine Water maze Learning Memory Hippocampus CA1 Rat
2015/9/23
Background: Reports on agmatine are controversial showing that it may improve memory, it can deteriorate memory and some did not notice any interference with learning and memory. In the present study,...
Adrenergic and cholinergic responses of the tracheal smooth muscle is enhanced during estrus phase in rat
Acetylcholine estradiol estrous cycle isoproterenol tracheal smooth muscle
2010/10/14
The aim of this study was to evaluate influences of hormonal changes during rat estrous cycle on airway responsiveness to bronchoconstrictor and bronchodilator agents. Materials and methods: The study...