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Inhibition of sweet chemosensory receptors alters insulin responses during glucose ingestion in healthy adults: a randomized crossover interventional study
sweet taste receptors lactisole glucose intolerance insulin saccharin artificial sweeteners OGTT modeling analysis
2018/11/13
Background: Glucose is a natural ligand for sweet taste receptors (STRs) that are expressed on the tongue and in the gastrointestinal tract. Whether STRs directly contribute to the regulation of gluco...
2017年IGF和胰岛素系统的生理学和疾病戈登学术会议（The Gordon Research Conference (GRC) on IGF & Insulin System in Physiology & Disease）
Physiology Disease
2017/1/19
The 2017 Gordon Conference on the Insulin-Like Growth Factor (IGF) and Insulin System in Physiology and Disease will present cutting-edge research on the roles of IGFs and insulin and their signaling ...
Reformulating cereal bars: high resistant starch reduces in vitro digestibility but not in vivo glucose or insulin response; whey protein reduces glucose but disproportionately increases insulin
randomized clinical trial blood glucose humans insulinemic response postprandial glycemic response
2018/12/14
Background: Resistant starch (RS) and whey protein are thought to be effective nutrients for reducing glycemic responses.
Reformulating cereal bars: high resistant starch reduces in vitro digestibility but not in vivo glucose or insulin response; whey protein reduces glucose but disproportionately increases insulin
randomized clinical trial blood glucose humans insulinemic response postprandial glycemic response
2018/12/18
Background: Resistant starch (RS) and whey protein are thought to be effective nutrients for reducing glycemic responses.
Fructose acute effects on glucose, insulin, and triglyceride after a solid meal compared with sucralose and sucrose in a randomized crossover study
fructose insulin postprandial sucralose sucrose
2018/11/30
Background: Fructose, which is a sweetener with a low glycemic index, has been shown to elevate postprandial triglyceride compared with glucose. There are limited data on the effect of fructose in a s...
Comparing Simple Insulin Sensitivity Indices to the Oral Minimal Model Postexercise
EXERCISE INTENSITY INSULIN RESISTANCE GLUCOSE TOLERANCE
2017/4/13
Purpose: This study aims to establish whether changes in indices of insulin sensitivity (Si) derived from fasting glucose and an oral glucose tolerance test (OGTT) are comparable to Si determined by t...
Diet low in advanced glycation end products increases insulin sensitivity in healthy overweight individuals: a double-blind, randomized, crossover trial
glycotoxin insulin resistance insulin secretion obesity receptors for AGEs
2018/11/30
Background: The consumption of advanced glycation end products (AGEs) has increased because of modern food processing and has been linked to the development of type 2 diabetes in rodents.
Genetic Association Between Insulin Resistance And Total Cholesterol In Type 2 Diabetes Mellitus - A Preliminary Observation
Type 2 diabetes Insulin resistance McAuley index Dyslipidaemia
2015/7/31
We investigated the degree of genetic association between insulin resistance (IR) with type 2 diabetes mellitus (DM) and abnormalities in lipid metabolism in 42 patients. IR was assessed by fasting in...
Aspartame in conjunction with carbohydrate reduces insulin levels during endurance exercise
Aspartame Exercise Insulin Blood glucose
2015/7/24
As most sport drinks contain some form of non-nutritive sweetener (e.g. aspartame), and with the variation in blood glucose regulation and insulin secretion reportedly associated with aspartame, a fur...
Comparison of Lactate Threshold, Glucose, and Insulin Levels Between OLETF and LETO Rats After All-Out Exercise
NIDDM OLETF treadmill running all-out exercise lactate velocity of lactate threshold
2015/4/23
Otsuka Long-Evans Tokushima Fatty (OLETF) rats are an animal model for obesity and Non Insulin Dependent Diabetes Mellitus by hyperphagia. The lactate threshold (LT) is used to determinate aerobic cap...
Adipose Tissue Insulin Action and IL-6 Signaling after Exercise in Obese Mice
INFLAMMATION MACROPHAGE ACUTE EXERCISE ADIPOSE TISSUE
2017/4/20
Introduction: Adipose tissue insulin action is impaired in obesity and is associated with inflammation, macrophage infiltration, and polarization toward a proinflammatory phenotype. Acute exercise can...
Barriers to Insulin Initiation The Translating Research Into Action for Diabetes Insulin Starts Project
Type 2 Diabetes Insulin Medication Adherence
2014/12/11
OBJECTIVE Reasons for failing to initiate prescribed insulin (primary nonadherence) are poorly understood. We investigated barriers to insulin initiation following a new prescription. RESEARCH DESIGN ...
Getting Under the Skin of Clinical Inertia in Insulin Initiation: The Translating Research Into Action for Diabetes (TRIAD) Insulin Starts Project
diabetes insulin therapy clinical inertia clinical decision-making
2014/12/11
Purpose The purpose of this cross-sectional study is to explore primary care providers’ (PCPs) perceptions about barriers to initiating insulin among patients. Studies suggest that many patients with ...
Effect of Glucose–Insulin–Potassium Infusion on Mortality in Critical Care Settings: A Systematic Review and Meta-Analysis
Clinical research critical care emergency medicine clinical trials anesthesiology
2014/11/28
This study seeks to measure the treatment effect of glucose—insulin—potassium (GIK) infusion on mortality in critically ill patients. A systematic review of randomized controlled trials is conducted, ...
Comparison of insulin resistance by indirect methods - HOMA,QUICKI and McAuley - with fasting insulin in patients with type 2 diabetes in Galle,Sri Lanka:A pilot study
Insulin resistance McAuley index HOMA index QUICKI index Fasting insulin Type 2 diabetes mellitus
2015/8/31
Background: To investigate importance of fasting insulin (FI) as a diagnostic test for insulin resistance (IR) and to compare with other standard methods McAuley (McA), HOMA and QUICKI indices in Diab...