搜索结果: 1-15 共查到“临床医学 allergen”相关记录22条 . 查询时间(0.118 秒)
Expression of the Recombinant Major Allergen of Salsola kali Pollen (Sal k 1) and Comparison with Its Low-Immunoglobulin E-Binding Mutant
comparison expression mutant Sal k 1 Salsola kali
2010/11/12
Background: The inhalation of Salsola kali pollen is an important cause of pollinosis during summer and early fall throughout desert and semi-desert areas. Sal k 1 has been previously reported as a ma...
Allergen Immunotherapy in Asthma: Current Status and Future Perspectives
allergic asthma allergic conjunctivitis allergic rhinitis immunotherapy Th2 responses
2010/11/12
Allergen immunotherapy targets Th2 cells activated by specific allergens, which constitutes the basis of allergic disease. Therefore, this approach has therapeutic potential for a variety of allergic ...
Local Induction of a Specific Th1 Immune Response by Allergen Linked Immunostimulatory DNA in the Nasal Explants of Ragweed-Allergic Subjects
allergen allergic rhinitis CpG motif immunotherapy vaccination
2010/11/16
RW or Amb-a-1 increased the number of IL-4, IL-5, and IL-13 mRNA+ cells in the tissue compared to medium alone. AIC had similar cytokine mRNA reactivity as control tissue. AIC and TT increased IFNγ-mR...
Cloning and Expression of the Allergen Cro s 2 Profilin from Saffron (Crocus sativus)
allergy cloning Cro s 2 profilin recombinant allergen saffron
2010/11/16
Background: Profilin is a panallergen that is recognized by IgE in allergic patients. Allergy to saffron (Crocus sativus) pollen has been described in people exposed to its pollen. Saffron contains a ...
Hev b 6.02 Is the Most Important Allergen in Health Care Workers Sensitized Occupationally by Natural Rubber Latex Gloves
allergen health care workers latex allergy latex gloves skin prick test
2010/11/16
Background: Natural rubber latex (NRL) allergy is a common occupational disease in health care workers (HCW). However, few reports have compared the major allergen of HCWs to those in gloves that are ...
Allergen-specific T-cell Response in Patients with Phenytoin Hypersensitivity; Simultaneous Analysis of Proliferation and Cytokine Production by Carboxyfluorescein Succinimidyl Ester (CFSE) Dilution Assay
allergen-specific T cell CFSE dilution assay IFN-γ lymphocyte transformation test phenytoin hypersensitivity
2010/11/18
Phenytoin-specific proliferation may be detected with greater sensitivity by the CFSE dilution assay than the conventional LTT. The assay revealed that both CD4+ and CD4- T cells proliferated and prod...
Effect of Antihistamine Eye Drops on the Conjunctival Provocation Test with Japanese Cedar Pollen Allergen
allergen provocation test allergic conjunctivitis antihistamine eye drops Japanese cedar pollinosis ketotifen fumarate levocabastine hydrochloride
2010/11/19
Preadministration of antihistamine eye drops suppressed the symptoms induced by the allergen, which suggests that this is an effective early therapy for Japanese cedar pollinosis, if it is started bef...
Efficacy of Levocabastine Hydrochloride Ophthalmic Suspension in the Conjunctival Allergen Challenge Test in Japanese Subjects with Seasonal Allergic Conjunctivitis
allergen challenge test allergic conjunctivitis conjunctival itching levocabastine hydrochloride redness
2010/11/18
The mean itching score in the levocabastine-treated group was 0.08 ± 0.06, which was significantly lower than the mean score of 1.98 ± 0.16 in the vehicle group (P < 0.0001). The redness and chemosis...
Role of the LTB4/BLT1 Pathway in Allergen-induced Airway Hyperresponsiveness and Inflammation
airway responsiveness cytokines lipid mediators lung inflammation Tcells
2010/11/18
LTB4, a proinflammatory lipid mediator generated from arachidonic acid through the action of 5-lipoxygenase, has been known for over two decades and is implicated in a wide variety of inflammatory dis...
Interleukin-4 is involved in allergen-induced airway eosinophilic inflammation and bronchial hyperresponsiveness independent of genetic background
bronchial hyperresponsiveness eosinophils IgE interleukin-4 mice
2010/11/26
The role of interleukin (IL)-4 in the development of allergen-induced airway inflammation and bronchial hyperresponsiveness (BHR) is still controversial. To investigate the role of IL-4 in the develop...
Purification of a novel allergen (SAP-1), which induces allergic asthma, from the red soft coral (Alcyonium gracillimum)
allergic protein bronchial asthma IgE occupational allergy purification red soft coral
2010/11/26
The red soft coral that is found around the spiny lobster represents a major allergen and many fishermen, especially those that catch the spiny lobster, suffer from allergic symptoms. Therefore, in th...
A case of milk allergy that presented anaphylaxis after cutaneous contact with allergen
anaphylaxis atopic dermatitis cutaneous contact milk allergy
2010/11/25
Milk allergy in a 1-year and 8-month-old boy is reported. At 1 year and 1 month of age, the patient presented with anaphylaxis, including erythema, which was initially localized to the contact site of...
Effect of modified immunotherapy with an allergen-pullulan conjugate in patients with Japanese cedar pollinosis
eosinophil immunotherapy Japanese cedar pollinossis mast cell seasonal allergic rhinitis Th1 cytokine Th2 cytokine
2010/11/25
Immunologic mechanisms of allergen immunotherapy are still incompletely understood. Immunotherapy of a higher maximum tolerance dose with reduced risks of systemic reactions, such as anaphylaxis, need...
Allergen immunotherapy: Current and new therapeutic strategies
allergen IgE immunotherapy T cell
2010/11/24
Allergen-specific immunotherapy (SIT) involves the administration of gradually increasing amounts of an allergen extract to reduce clinical symptoms of allergy. Well-controlled clinical trials have de...
Immunologic determination of the major allergen, Cry j 1, in Cryptomeria japonica pollen of 117 clones in Toyama prefecture: Some implications for further forestry research in pollinosis prevention
Cry j 1 Cryptomeria japonica D. Don environmental factor genotype variation Japanese cedar pollinosis
2010/11/24
Background: A number of recent studies have clarified the characteristics of major allergens of Cryptomeria japonica, such as the locality, molecular weights of Cry j 1 and Cry j 2 and cross-reactivit...