搜索结果: 16-29 共查到“生物医学工程 mice”相关记录29条 . 查询时间(0.184 秒)
Effects of metallothionein on the concentrations of trace elements in mice under the stress conditions
Metallothionein Stress Trace elements Zinc Manganese Molybdenum
2009/4/1
Our object of this study was to investigate the effects of metallothionein, metal binding protein, on the change of the tissue distribution of essential metals by restraint stress. Wild-type and MT-nu...
Protective effect of metallogluconates against UVA-induced cutaneous lesion in HR-1 hairless mice
skin UVA reactive oxygen species(ROS) inflammation
2009/4/1
UVA-induced reactive oxygen species (ROS) generation is well known to cause cutaneous lesion in the skin, therefore, it is important to prevent the skin from UV damage due to ROS generation. In 2000, ...
The physiological effects of the undercurrent water from Mt. Fuji on type 2 diabetic KK-Ay mice
physiological effects undercurrent water Mt. Fuji
2009/4/1
Recently, it has been reported that vanadium exists in a relatively high concentration in the natural water around Mt. Fuji in Japan. Vanadium is known to have a blood glucose lowering effect and impr...
Normalizing Effect of Zinc（II）Complex with 6-Ethoxy Picolinic Acid on Blood Glucose Levels in KK-Ay Mice
diabetes Zn(II) complex KK-Ay blood glucose level
2009/3/23
We examined normalizing effect for blood glucose levels of zinc(II) complex with 6-ethoxy picolinic acid (Zn(6-EtOpa)2) on KK-Ay mice which used in this study as the model animals of type 2 diabetes, ...
Interferon-gamma liniment protects hairless mice against ultraviolet irradiation-induced skin damage
Interferon-gamma liniment protects hairless mice ultraviolet irradiation-induced skin damage
2009/3/3
Ultraviolet B (UVB) irradiation has been reported as one of causes of epidermal carcinoma and also one of immunosuppressive inducers associated with an up-regulated production of T helper (Th) 2-typ...
Expansion of NK1.1− intermediate TCR cells and granulocytes in mice transplanted with TAP-1-deficient cells
NK1.1− intermediate TCR cells granulocytes mice transplanted TAP-1-deficient cells
2009/3/3
Missing self which lacked the expression of MHC class I antigens was prepared in irradiated B6.Ly5.1 mice (H-2b) which had undergone bone marrow transplantation (BMT) (depleted of T cells) of TAP-1 ...
Comparative characterization of double-positive CD4+8+ cells in the thymus and small intestine of mice
Comparative characterization double-positive CD4+8+ cells small intestine of mice
2009/3/3
This study focused on double-positive (DP) CD4+8+ cells in both the intestine and thymus. In normal mice, the proportion of DP cells in the intestine increased with aging, while that of DP cells in ...
Localization of 3-phosphoglycerate dehydrogenase, an enzyme involved in de novo L-serine biosynthesis, in the peripheral nervous system and non-neuronal tissues of mice
3-phosphoglycerate dehydrogenase novo L-serine biosynthesis peripheral nervous system
2009/3/3
The non-essential amino acid L-serine is biosynthesized from 3-phosphoglycerate by astrocytes, and functions as a key mediator of neurotrophic support in the brain. In the present study, the cellula...
Eye-concentrated distribution of dexamethasone carried by sugar-chain modified liposome in experimental autoimmune uveoretinitis mice
Eye-concentrated distribution dexamethasone sugar-chain modified liposome experimental autoimmune uveoretinitis mice
2009/3/2
Corticosteroid is generally accepted as a standard therapeutic agent for active inflammatory (and) autoimmune eye diseases. In an attempt to develop a system to deliver corticosteroid most efficient...
Influences of reduced masticatory sensory input from soft-diet feeding upon spatial memory/learning ability in mice
reduced masticatory sensory soft-diet feeding spatial memory/learning ability mice
2009/3/2
It has been reported that reduction of masticatory afferent stimulation might influence learning and memory function. In order to clarify the influences of reduced masticatory sensory input on spatial...
Brain-derived neurotrophic factor（BDNF）prevents the development of diabetes in prediabetic mice
Brain-derived neurotrophic factor (BDNF) diabetes prediabetic mice
2009/3/2
We previously reported that peripheral injection of brain-derived neurotrophic factor (BDNF) exhibits hypophagic and hypoglycemic effects in obese hyperglycemic animals, indicating its antiobesi...
Urothelium EP1 receptor facilitates the micturition reflex in mice
Urothelium EP1 micturition reflex mice
2009/3/2
We investigated the presence of EP1 receptor in the urothelium and its role in micturition reflex by examining the effect of intravesical administration of prostaglandin E2 (PGE2), an EP1 agonist (O...
The effect of neonatal capsaicin treatment on the CGRP-immunoreaction in the trigeminal subnucleus caudalis of mice
neonatal capsaicin treatment CGRP-immunoreaction trigeminal subnucleus caudalis mice
2009/3/2
The calcitonin-gene related peptide (CGRP) is a primary afferent neurotransmitter in the trigeminal system. Although a neonatal administration of capsaicin eliminates substance P (SP)-mediated nocic...
Assessment of a non-invasive high-throughput classifier for behaviours associated with sleep and wake in mice
a non-invasive high-throughput classifier behaviours sleep and wake mice
2010/2/25
This work presents a non-invasive high-throughput system for automatically detecting characteristic behaviours in mice over extended periods of time, useful for phenotyping experiments. The system cla...