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The noninvasive assessment of cardiac function is of first importance for the diagnosis of cardiovascular diseases. Among all medical scanners only a few enables radiologists to evaluate the local car...
We developed an empirical PET model taking into account system blurring and a blind iterative reconstruction scheme that estimates both the actual image and the point spread function of the system. Re...
Elastography is developed as a quantitative approach to imaging linear elastic properties of tissues to detect suspicious tumors. In this paper a nonlinear elastography method is introduced for recons...
Thermal properties of biological tissues play a critical role in the study of tumor angiogenesis and the design and monitoring of thermal therapies. To map thermal parameters noninvasively, we propose...
Three-dimensional Oximetric Electron Paramagnetic Resonance Imaging using the Single Point Imaging modality generates unpaired spin density and oxygen images that can readily distinguish between norma...
Image registration is a crucial step in many medical image analysis procedures such as image fusion, surgical planning, segmentation and labeling, and shape comparison in population or longitudinal st...
We propose a constrained version of Mumford and Shah's (1989) segmentation model with an information-theoretic point of view in order to devise a systematic procedure to segment brain magnetic resonan...
Currently, 3D cone-beam CT image reconstruction speed is still a severe limitation for clinical application. The computational power of modern graphics processing units (GPUs) has been harnessed to pr...
We developed a new magnetic sensor for residual brain tumor using magnetite enveloped by cationic liposome (MCL) . First, we evaluated the dynamic state of MCL on MRI following local injection into th...
We have been working on development of automated preoperative planning system for total hip arthroplasty. Although we have already developed automated planning procedures for implants which are insert...
Mechanical stress is known to alter the electrophysiological property of myocardium and may trigger fatal arrhythmias when an abnormal load is applied to the heart. We developed novel techniques combi...
Our goal is to establish an early diagnostic method for dementia by electroencephalography (EEG) usinga working memory task (Sternberg task). We studied four dementia patients and eighteen healthy sub...
An “active” ultrasound Doppler method was newly developed in order to directly and easily discriminate emboli from micro bubbles flowing in blood vessel. The principle of this method is based on measu...
Hyperthermia treatment incorporating magnetic nanoparticles (MNPs) is a hopeful therapy for cancers. Acquiring information about the MNPs’ deposition in tumor tissues and modeling magnetic heating in ...
Controllable bio-synthetic polymeric hydrogels made from fibrinogen-poly(ethylene glycol) adducts have been successfully employed in tissue engineering. The structural consequences of PEG conjugati...

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